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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN SUGI
CommentsMb3364, sugI, len: 502 aa. Equivalent to Rv3331,len: 502 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 502 aa overlap). Probable sugI,sugar-transport integral membrane protein, possibly member of major facilitator superfamily (MFS), similar to several transporters e.g. P37021|GALP_ECOLI|B2943 GALACTOSE-PROTON SYMPORTER (GALACTOSE TRANSPORTER) from Escherichia coli strain K12 (464 aa), FASTA scores: opt: 818, E(): 1.8e-39,(31.85% identity in 446 aa overlap); P96742|YWTG METABOLITE-TRANSPORT-RELATED PROTEIN from Bacillus subtilis (457 aa), FASTA scores: opt: 810, E(): 5e-39,(33.2% identity in 428 aa overlap); AAG58074|GALP (alias BAB37242|ECS3819) GALACTOSE-PROTON SYMPORT OF TRANSPORT SYSTEM from Escherichia coli strain O157:H7 EDL933 (464 aa), FASTA scores: opt: 810, E(): 5.1e-39, (32.2% identity in 432 aa overlap); P46333|CSBC_BACSU|SS92BR PROBABLE METABOLITE TRANSPORT PROTEIN from Bacillus subtilis (461 aa), FASTA scores: opt: 792, E(): 5.4e-38, (33.7% identity in 442 aa overlap); etc. Equivalent to AAK47777|MT343 from Mycobacterium tuberculosis strain CDC1551 (500 aa) but with some divergence between residues 229 and 254. Contains PS00216 Sugar transport proteins signature 1 and PS00217 Sugar transport proteins signature 2. BELONGS TO THE SUGAR TRANSPORTER FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36743393675847+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3364|sugI
MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRRALLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTTAVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSGIVVGYLVGYLLAGSHGWRAMFGLAAAPATLLLPLLWRMPDTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVDERGGGIGEMVRRPYLRATLFVIALGFLVQITGINAIIYYSPRLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSGIATMITADAVLITVFANDSDGGTGLVLGFAGVLLFIIGFNFGFGSLVWVYAAESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRVLGGAGVFAVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAADEP
      
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