Gene Mb3367
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MERR-FAMILY) |
| Comments | Mb3367, -, len: 146 aa. Equivalent to Rv3334, len: 146 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 146 aa overlap). Probable transcriptional regulator, similar to many regulatory proteins (notably mercury resistance operon regulators) e.g. Q9HXV1|PA3689 PROBABLE TRANSCRIPTIONAL REGULATOR MERR FAMILY from Pseudomonas aeruginosa (156 aa), FASTA scores: opt: 275, E(): 1.6e-11, (35.95% identity in 139 aa overlap); Q9AKR6|PBRR LEAD RESISTANCE OPERON REGULATOR from Ralstonia metallidurans strain CH34 (plasmid pMOL30) (145 aa), FASTA scores: opt: 267, E(): 5.2e-11, (35.8% identity in 134 aa overlap); P95838|MERR MERCURIC RESISTANCE OPERON REGULATOR from Synechococcus sp. strain PCC 7942 (Anacystis nidulans R2) (144 aa), FASTA scores: opt: 266, E(): 6e-11, (31.35% identity in 118 aa overlap); P22853|MERR_BACSR MERCURIC RESISTANCE OPERON REGULATOR from Bacillus sp. strain RC607 (132 aa), FASTA scores: opt: 262, E(): 1e-10, (34.6% identity in 130 aa overlap); etc. Contains probable helix-turn-helix motif at aa 1-22 (Score 1478, +4.22 SD). SEEMS TO BELONG TO THE MERR FAMILY OF TRANSCRIPTIONAL REGULATORS. |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3678506 | 3678946 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3367|Mb3367
MKISEVAALTNTSTKTLRFYENSGLLPPPARTASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAPCAHVRQLLSTRIDEVRAQIAELIALEGHLQTLLDHASYGPPTEHDHSTVCWILESDLDEPTAIEVSDIHA
Bibliography
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