Gene Mb3457c in Mycobacterium bovis AF2122/97
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namealr
Gene length1227 bp
IdentifierMb3457c
Location 3792822 bp
Protein summary information
Molecular mass43387.7 Da
Isoelectric point6.5159
Protein length408 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_003637
M. tuberculosis H37RvRv3423c
Cross-references
UniProtKB/TrEMBLX2BNP3, P0A4X3
SWISS-MODELP0A4X3
General annotation
TypeCDS
FunctionUnknown
Productalanine racemase alr
CommentsMb3457c, alr, len: 408 aa. Equivalent to Rv3423c,len: 408 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 408 aa overlap). Probable alr, alanine racemase (EC 5.1.1.1), equivalent to P38056|ALR_MYCLE|ML0375|B229_C3_243 ALANINE RACEMASE from Mycobacterium leprae (388 aa), FASTA scores: opt: 2160,E(): 2.3e-124, (84.35% identity in 384 aa overlap). Also highly similar to other alanine racemases e.g. Q9L888|ALR_MYCAV from Mycobacterium avium (391 aa), FASTA scores: opt: 2103, E(): 6.8e-121, (83.6% identity in 384 aa overlap); P94967|ALR_MYCSM from M. smegmatis (389 aa),FASTA scores: opt: 1721, E(): 1.3e-97, (67.25% identity in 385 aa overlap); O86786|ALR_STRCO|SC6G4.23 from Streptomyces coelicolor (391 aa), FASTA scores: opt: 1041,E(): 3.7e-56, (47.65% identity in 380 aa overlap); etc. BELONGS TO THE ALANINE RACEMASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS37928223794048-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3457c|alr
MKRFWENVGKPNDTTDGRGTTSLAMTPISQTPGLLAEAMVDLGAIEHNVRVLREHAGHAQLMAVVKADGYGHGATRVAQTALGAGAAELGVATVDEALALRADGITAPVLAWLHPPGIDFGPALLADVQVAVSSLRQLDELLHAVRRTGRTATVTVKVDTGLNRNGVGPAQFPAMLTALRQAMAEDAVRLRGLMSHMVYADKPDDSINDVQAQRFTAFLAQAREQGVRFEVAHLSNSSATMARPDLTFDLVRPGIAVYGLSPVPALGDMGLVPAMTVKCAVALVKSIRAGEGVSYGHTWIAPRDTNLALLPIGYADGVFRSLGGRLEVLINGRRCPGVGRICMDQFMVDLGPGPLDVAEGDEAILFGPGIRGEPTAQDWADLVGTIHYEVVTSPRGRITRTYREAENR
Bibliography
No article yet recorded