Gene Mb3471c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE PHOSPHO-SUGAR MUTASE / MRSA PROTEIN HOMOLOG |
| Comments | Mb3471c, mrsA, len: 448 aa. Equivalent to Rv3441c,len: 448 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 448 aa overlap). Probable mrsA,phosphoglucomutase or phosphomannomutase (EC 5.4.2.-),equivalent to Q49869|URED|B229_C3_234 MRSA PROTEIN HOMOLOG from Mycobacterium leprae (463 aa), FASTA scores: opt: 2449, E(): 6.3e-135, (87.65% identity in 445 aa overlap); and highly similar (but longer 178 aa) to Q49862|UREC|B229_C2_192 PUTATIVE UREASE OPERON UREC PROTEIN from Mycobacterium leprae (288 aa), FASTA scores: opt: 1442, E(): 1.3e-76, (86.5% identity in 267 aa overlap). Highly similar to phospho-sugar mutases e.g. Q53876|SC6G4.14 PUTATIVE PHOSPHO-SUGAR MUTASE (SIMILAR TO PHOSPHOMANNOMUTASES) from Streptomyces coelicolor (452 aa), FASTA scores: opt: 1710, E(): 5e-92, (60.45% identity in 450 aa overlap); Q9KG46|BH0267 PHOSPHOGLUCOSAMINE MUTASE from Bacillus halodurans (447 aa), FASTA scores: opt: 1351, E(): 3.5e-71, (48.4% identity in 444 aa overlap); BAB58323|GLMM PHOSPHOGLUCOSAMINE-MUTASE from Staphylococcus aureus subsp. aureus Mu50 (451 aa) and Q99QR5|GLMM(FEMD)|SA1965 PHOSPHOGLUCOSAMINE-MUTASE from Staphylococcus aureus subsp. aureus N315. (451 aa), FASTA scores: opt: 1315, E(): 4.3e-69, (48.45% identity in 446 aa overlap); P95685|FEMD|GLMM PHOSPHOGLUCOSAMINE-MUTASE (451 aa), FASTA scores: opt: 1310, E(): 8.5e-69, (48.2% identity in 446 aa overlap); P95575|MRSA_PSESY MRSA PROTEIN HOMOLOG from Pseudomonas syringae (pv. syringae) (447 aa), FASTA scores: opt: 1143, E(): 4.2e-59, (42.75% identity in 447 aa overlap); etc. Contains PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. BELONGS TO THE PHOSPHOHEXOSE MUTASES FAMILY. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3807726 | 3809072 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3471c|mrsA
MGRLFGTDGVRGVANRELTAELALALGAAAARRLSRSGAPGRRVAVLGRDPRASGEMLEAAVIAGLTSEGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDDTEDQIEDLVLGVSRGPGLRPAGAGIGRVIDAEDATERYLRHVAKAATARLDDLAVVVDCAHGAASSAAPRAYRAAGARVIAINAEPNGRNINDGCGSTHLDPLRAAVLAHRADLGLAHDGDADRCLAVDANGDLVDGDAIMVVLALAMKEAGELACNTLVATVMSNLGLHLAMRSAGVTVRTTAVGDRYVLEELRAGDYSLGGEQSGHIVMPALGSTGDGIVTGLRLMTRMVQTGSSLSDLASAMRTLPQVLINVEVVDKATAAAAPSVRTAVEQAAAELGDTGRILLRPSGTEPMIRVMVEAADEGVAQRLAATVADAVSTAR
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