Gene Mb3525c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E) |
| Comments | Mb3525c, lprN, len: 384 aa. Equivalent to Rv3495c,len: 384 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 384 aa overlap). Possible lprN (alternate gene name: mce4E), lipoprotein which belongs to 24-membered Mycobacterium tuberculosis Mce protein family (see citations below for more information), highly similar to Mycobacterium tuberculosis proteins O07417|LPRK|Rv0173|MTCI28.13|mce1E (390 aa); O07785|LPRL|Rv0593|MTCY19H5.29|mce2E (402 aa); and O53971|LPRM|Rv1970|MTV051.08|mce3E (377 aa). Also similar to others e.g. Q9F360|SC8A2.03c PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (413 aa), FASTA scores: opt: 656, E(): 2.2e-32, (37.55% identity in 317 aa overlap); Q9CD10|LPRK|ML2593 PUTATIVE LIPOPROTEIN from Mycobacterium leprae (392 aa), FASTA scores: opt: 616, E(): 5.5e-30,(28.95% identity in 373 aa overlap); etc. Contains possible signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3859003 | 3860157 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3525c|lprN
MNRIWLRAIILTASSALLAGCQFGGLNSLPLPGTAGHGEGAYSVTVEMADVATLPQNSPVMVDDVTVGSVAGIVAVQRPDGSFYAAVKLDLDKNVLLPANAVAKVSQTSLLGSLHVELAPPTDRPPTGRLVDGSRITEANTDRFPTTEEVFSALGVVVNKGNVGALEEIIDETHQAVAGRQAQFVNLVPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAVRVLNQNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALNDDRKDFVTSLQLLLTFPFPNFGIKQAVRGDYLNVFTTFDLTLRRIGETFFTTAYFDPNMAHMDEILNPPDFLIGELANLSGQAADPFKIPPGTASGQ
Bibliography
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