Gene Mb3532c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable short-chain type dehydrogenase/reductase. possible 17-beta-hydroxysteroid dehydrogenase. |
| Comments | Mb3532c, -, len: 317 aa. Equivalent to Rv3502c,len: 317 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 317 aa overlap). Probable short-chain dehydrogenase/reductase (EC 1.-.-.-), similar to Mycobacterium tuberculosis proteins P71853|Rv3548c|MTCY03C7.08 HYPOTHETICAL 31.1 KDA PROTEIN (304 aa), FASTA scores: opt: 739, E(): 6.2e-35, (45.15% identity in 310 aa overlap); and Q11020|YD50_MYCTU|FABG2|Rv1350|MT1393|MTCY02B10.14 PUTATIVE OXIDOREDUCTASE (247 aa), FASTA scores: opt: 475,E(): 5.1e-20, (40.15% identity in 254 aa overlap). Also similar to various dehydrogenases e.g. Q9I4V1|PA1023 PROBABLE SHORT-CHAIN DEHYDROGENASE from Pseudomonas aeruginosa (305 aa), FASTA scores: opt: 535, E(): 2.3e-23,(37.1% identity in 302 aa overlap); Q9UVH9|FOX2 FOX2 PROTEIN (SDR FAMILY) (1015 aa), FASTA scores: opt: 487,E(): 3.2e-20, (38.4% identity in 276 aa overlap); P22414|FOX2_CANTR PEROXISOMAL HYDRATASE-DEHYDROGENASE,D-3-HYDROXYACYL CoA DEHYDROGENASE (EC 1.1.1.-) (SDR FAMILY) from Candida tropicalis (Yeast) (906 aa) FASTA scores: opt: 481, E(): 6.4e-20, (38.0% identity in 250 aa overlap); P50171|DHB8_MOUSE|HSD17B8|HKE6|H2-KE6 ESTRADIOL 17 BETA-DEHYDROGENASE 8 from Mus musculus (Mouse) (260 aa) FASTA scores: opt: 459, E(): 4.3e-19, (39.75% identity in 259 aa overlap); CAC41362|BKR1 3-OXYACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC 1.1.1.100) (FRAGMENT) from Brassica napus (Rape) (317 aa), FASTA scores: opt: 447, E(): 2.4e-18, (39.2% identity in 255 aa overlap); etc. Contains PS00061 Short-chain dehydrogenases/reductases family signature. BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY. Start uncertain. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3866710 | 3867663 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3532c|Mb3532c
MKLTESNRSPRTTNTTDLSGKVAVVTGAAAGLGRAEALGLARLGATVVVNDVASALDASDVVDEIGAAAADAGAKAVAVAGDISQRATADELLASAVGLGGLDIVVNNAGITRDRMLFNMSDEEWDAVIAVHLRGHFLLTRNAAAYWRDKAKDAEGGSVFGRLVNTSSEAGLVGPVGQANYAAAKAGITALTLSAARALGRYGVCANVICPRARTAMTADVFGAAPDVEAGQIDPLSPQHVVSLVQFLASPAAAEVNGQVFIVYGPQVTLVSPPHMERRFSADGTSWDPTELTATLRDYFAGRDPEQSFSATDLMRQ
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