Gene Mb3544c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | fatty-acid-coa ligase fadd19 (fatty-acid-coa synthetase) (fatty-acid-coa synthase) |
| Comments | Mb3544c, fadD19, len: 548 aa. Equivalent to Rv3515c, len: 548 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 548 aa overlap). Probable fadD19, fatty-acid-CoA synthetase (EC 6.2.1.-),similar (or with similarity) to many e.g. Q9EXL2|FADD FADD PROTEIN from Streptomyces griseus (540 aa), FASTA scores: opt: 1449, E(): 1.5e-81, (46.0% identity in 535 aa overlap); AAB87139|MIG MEDIUM CHAIN ACYL-COA SYNTHETASE PRECURSOR from Mycobacterium avium (550 aa), FASTA scores: opt: 1226, E(): 7.6e-68, (40.7% identity in 543 aa overlap); Q9A7C3|CC1801 PUTATIVE 4-COUMARATE--COA LIGASE from Caulobacter crescentus (561 aa), FASTA scores: opt: 979, E(): 1.2e-52, (34.05% identity in 531 aa overlap); O28502|AF1772 LONG-CHAIN-FATTY-ACID--COA LIGASE (FADD-7) from Archaeoglobus fulgidus (569 aa), FASTA scores: opt: 560, E(): 6.9e-27, (29.3% identity in 543 aa overlap); Q9A8N2|CC1321 LONG-CHAIN-FATTY-ACID--COA LIGASE from Caulobacter crescentus (583 aa), FASTA scores: opt: 544,E(): 6.7e-26, (27.2% identity in 518 aa overlap); P29212|LCFA_ECOLI|FADD|OLDD|B1805 LONG-CHAIN-FATTY-ACID--COA LIGASE from Escherichia coli strain K12 (561 aa), FASTA scores: opt: 460, E(): 4e-22,(26.3% identity in 567 aa overlap); etc. Contains PS00455 Putative AMP-binding domain signature. Note that upstream MTV023.20c|Rv3513c|fadD18 is identical to C-terminal part of FADD19|Rv3515c|MTV023.22c (probably result of partial gene duplication). |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3894040 | 3895686 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3544c|fadD19
MAVALNIADLAEHAIDAVPDRVAVICGDEQLTYAQLEDKANRLAHHLIDQGVQKDDKVGLYCRNRIEIVIAMLGIVKAGAILVNVNFRYVEGELRYLFDNSDMVALVHERRYADRVANVLPDTPHVRTILVVEDGSDQDYRRYGGVEFYSAIAAGSPERDFGERSADAIYLLYTGGTTGFPKGVMWRHEDIYRVLFGGTDFATGEFVKDEYDLAKAAAANPPMIRYPIPPMIHGATQSATWMALFSGQTTVLAPEFNADEVWRTIHKHKVNLLFFTGDAMARPLVDALVKGNDYDLSSLFLLASTAALFSPSIKEKLLELLPNRVITDSIGSSETGFGGTSVVAAGQAHGGGPRVRIDHRTVVLDDDGNEVKPGSGMRGVIAKKGNIPVGYYKDEKKTAETFRTINGVRYAIPGDYAQVEEDGTVTMLGRGSVSINSGGEKVYPEEVEAALKGHPDVFDALVVGVPDPRYGQQVAAVVQARPGCRPSLAELDSFVRSEIAGYKVPRSLWFVDEVKRSPAGKPDYRWAKEQTEARPADDVHAGHVTSGG
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