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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE COENZYME F420-DEPENDENT OXIDOREDUCTASE
CommentsMb3550c, -, len: 347 aa. Equivalent to Rv3520c,len: 347 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 347 aa overlap). Possible coenzyme F420-dependent oxidoreductase (EC 1.-.-.-), equivalent to Q9CCV8|ML0348 POSSIBLE COENZYME F420-DEPENDENT OXIDOREDUCTASE from Mycobacterium leprae (350 aa), FASTA scores: opt: 2029, E(): 9.1e-120, (86.85% identity in 342 aa overlap). Similar to many coenzyme F420-dependent enzymes (and other proteins) e.g. Q9AD98|SCI52.11c PUTATIVE ATP/GTP-BINDING PROTEIN from Streptomyces coelicolor (351 aa), FASTA scores: opt: 859, E(): 1.6e-46,(41.9% identity in 346 aa overlap); Q9X7Y1|SC6A5.35 PUTATIVE OXIDOREDUCTASE from Streptomyces coelicolor (341 aa), FASTA scores: opt: 800, E(): 7.9e-43, (38.95% identity in 339 aa overlap); Q9ZA30|GRA-ORF29 PUTATIVE FMN-DEPENDENT MONOOXYGENASE from Streptomyces violaceoruber (343 aa), FASTA scores: opt: 354, E(): 6.7e-15, (34.2% identity in 336 aa overlap); Q49598|MER COENZYME F420-DEPENDENT N5,N10-METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE from Methanopyrus kandleri (349 aa), FASTA scores: opt: 283,E(): 1.9e-10, (26.75% identity in 329 aa overlap); Q58929|MER|MJ1534 F420-DEPENDENT METHYLENETETRAHYDROMETHANOPTERIN REDUCTASE from Methanococcus jannaschii (331 aa), FASTA scores: opt: 227,E(): 5.8e-07, (26.35% identity in 334 aa overlap); O27784|MTH1752 COENZYME F420-DEPENDENT N5,N10-METHYLENE TETRAHYDROMETHANOPTERIN REDUCTASE from Methanobacterium thermoautotrophicum (321 aa), FASTA scores: opt: 207, E(): 1e-05, (27.4% identity in 336 aa overlap); etc. Also similar to Q11030|YD60_MYCTU|Rv1360|MT1405|MTCY02B10.24 HYPOTHETICAL 37.3 KDA PROTEIN from Mycobacterium tuberculosis (340 aa), FASTA scores: opt: 313, E(): 2.5e-12, (28.0% identity in 311 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS38995403900583-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3550c|Mb3550c
MEAGMKLGLQLGYWGAQPPQNHAELVAAAEDAGFDTVFTAEAWGSDAYTPLAWWGSSTQRVRLGTSVIQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQRFPKPLARTREYIDIVRQVWARESPVTSAGPHYRLPLTGEGTTGLGKALKPITHPLRADIPIMLGAEGPKNVALAAEICDGWLPIFYSPRMAGMYNEWLDEGFARPGARRSREDFEICATAQVVITDDRAAAFAGIKPFLALYMGGMGAEETNFHADVYRRMGYTQVVDEVTKLFRSGRKDEAAEIIPDELVDDAVIVGDIDHVRKQMAVWEAAGVTMMVVTAGSAEQVRDLAALV
      
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