Gene Mb3552 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameltp4
Gene length1065 bp
IdentifierMb3552
Location 3901663 bp
Protein summary information
Molecular mass37877.0 Da
Isoelectric point6.3753
Protein length354 amino acids
Orthologs
M. tuberculosis H37RvRv3522
M. tuberculosis MTBC0mtbc0_003738
Cross-references
InterProIPR002155, IPR016038, IPR016039
UniProtKB/TrEMBLQ7TWA9
SWISS-MODELA0A1R3Y4H2
General annotation
TypeCDS
FunctionUnknown
Productpossible lipid transfer protein or keto acyl-coa thiolase ltp4
CommentsMb3552, -, len: 354 aa. Equivalent to Rv3522, len: 354 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 354 aa overlap). Possible lipid carrier protein or keto acyl-CoA thiolase (EC 2.3.1.16), similar to several e.g. O30103|AF0134 3-KETOACYL-COA THIOLASE (ACAB-4) from Archaeoglobus fulgidus (398 aa) FASTA scores: opt: 352, E(): 5.3e-15, (30.45% identity in 381 aa overlap); O29295|AF0967 3-KETOACYL-COA THIOLASE (ACAB-9) from Archaeoglobus fulgidus (400 aa) FASTA scores: opt: 312, E(): 1.8e-12, (28.05% identity in 367 aa overlap); O29294|AF0968 3-KETOACYL-COA THIOLASE (ACAB-10) from Archaeoglobus fulgidus (388 aa), FASTA scores: opt: 293,E(): 2.9e-11, (25.9% identity in 309 aa overlap); O58409|PH0676 LONG HYPOTHETICAL NONSPECIFIC LIPID-TRANSFER PROTEIN (ACETHYL CoA SYNTHETASE) (EC 6.2.1.-) from Pyrococcus horikoshii (389 aa), FASTA scores: opt: 292,E(): 3.3e-11, (25.8% identity in 368 aa overlap); Q9Y9A3|APE2382 LONG HYPOTHETICAL NON SPECIFIC LIPID-TRANSFER PROTEIN from Aeropyrum pernix (360 aa) FASTA scores: opt: 270, E(): 7.8e-10, (27.25% identity in 363 aa overlap); Q9YDI4|APE0929 LONG HYPOTHETICAL NONSPECIFIC LIPID-TRANSFER PROTEIN from Aeropyrum pernix (400 aa), FASTA scores: opt: 258, E(): 4.9e-09, (26.45% identity in 306 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39016633902727+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3552|ltp4
MSVRDIAVVGFAHAPHVRRTDGTTNGVEMLMPCFAQLYDELGITKADIGFWCSGSSDYLAGRAFSFISAIDSIGAVPPINESHVEMDAAWALYEAYIKLLTGEVDTALVYGFGKSSAGTLRRVLSRQTDPYTVAPLWPDSVSMAGLQARLGLDSGKWTHEQMARVAFDSFTNARRVDSVEPPITVGELLARPFFADPLRRHDIAPITDGAAAVVLAADNRARELRENPAWITGIEHRIESPALGARDITESPSTKLAAKIATGGHTGDIDVAEIHGPFTHQHLIVAEAIRIPGKTKVNPSGGPLAANPMFAAGLERIGFAAQHIWDGSARRVLAHATSGPALQQNLVAVMEGRG
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