Gene Mb3581
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE COA-TRANSFERASE (ALPHA SUBUNIT) |
| Comments | Mb3581, -, len: 292 aa. Equivalent to Rv3551, len: 292 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 292 aa overlap). Possible CoA-transferase, alpha subunit (EC 2.8.3.-), similar in part to other CoA-transferases e.g. Q59111|GCTA_ACIFE|GCTA GLUTACONATE COA-TRANSFERASE SUBUNIT A (EC 2.8.3.12) (GCT LARGE SUBUNIT) from Acidaminococcus fermentans (319 aa) FASTA scores: opt: 247, E(): 6.3e-09, (27.35% identity in 307 aa overlap); Q9XD83|PCAI from Streptomyces sp. 2065 (251 aa), FASTA scores: opt: 222, E(): 2.3e-07, (27.55% identity in 243 aa overlap); BAB50895|MLL4183 from Rhizobium loti (Mesorhizobium loti) (285 aa), FASTA scores: opt: 206, E(): 2.8e-06, (27.4% identity in 281 aa overlap); etc. Also some similarity with O06167|SCOA_MYCTU|RVv504c|MT2579|MTCY07A7.10c PROBABLE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE SUBUNIT A from Mycobacterium tuberculosis (248 aa), FASTA scores: opt: 210, E(): 1.4e-06, (25.5% identity in 247 aa overlap). BELONGS TO THE GLUTACONATE COA-TRANSFERASE SUBUNIT A FAMILY. Note that this putative protein may combine with the putative protein encoded by the downstream ORF Rv3552 to form a CoA-transferase that comprises two subunits. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3933111 | 3933989 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3581|Mb3581
MPDKRTSLDDAVAQLRSGMTIGIAGWGSRRKPMAFVRAILRSDVTDLTVVTYGGPDLGLLCSAGKVKRVYYGFVSLDSPPFYDPWFAHARTSGAIEAREMDEGMLRCGLQAAAQRLPFLPIRAGLGSSVPQFWAGELQTVTSPYPAPGGGYETLIAMPALRLDAAFAHLNLGDSHGNAAYTGIDPYFDDLFLMAAERRFLSVERIVATEELVKSVPPQALLVNRMMVDAIVEAPGGAHFTTAAPDYGRDEQFQRHYAEAASTQVGWQQFVHTYLSGTEADYQAAVHNFGASR
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