Gene Mb3583 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3583
Gene length1068 bp
IdentifierMb3583
Location 3934836 bp
Protein summary information
Molecular mass36830.8 Da
Isoelectric point9.8633
Protein length355 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_003770
M. tuberculosis H37RvRv3553
Cross-references
InterProIPR004136, IPR013785
UniProtKB/TrEMBLQ7TW81
SWISS-MODELA0A1R3Y4H7
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE OXIDOREDUCTASE
CommentsMb3583, -, len: 355 aa. Equivalent to Rv3553, len: 355 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 355 aa overlap). Possible oxidoreductase (EC 1.-.-.-), highly similar (except in C-terminus) to Q9A327|CC3379 HYPOTHETICAL PROTEIN from Caulobacter crescentus (321 aa), FASTA scores: opt: 639,E(): 4.6e-29, (46.35% identity in 248 aa overlap); and Q9WZQ7|TM0800 CONSERVED HYPOTHETICAL PROTEIN from Thermotoga maritima (314 aa), FASTA scores: opt: 622, E(): 4.1e-28, (37.95% identity in 340 aa overlap). Also similar to two TRANS-2-ENOYL-ACP REDUCTASES; Q99YD4|FABK|SPY1751 from Streptococcus pyogenes (323 aa), FASTA scores: opt: 604, E(): 4.4e-27, (33.25% identity in 346 aa overlap); and Q9FBC5|FABK from Streptococcus pneumoniae (324 aa),FASTA scores: opt: 553, E(): 3.3e-24, (32.1% identity in 346 aa overlap); and similar with several 2-NITROPROPANE DIOXYGENASES, e.g. Q9F7P8 from uncultured proteobacterium EBAC31A08 (322 aa), FASTA scores: opt: 505, E(): 1.7e-21,(33.6% identity in 348 aa overlap); Q9FMG0 (alias AAK44141) from Arabidopsis thaliana (Mouse-ear cress) (333 aa), FASTA scores: opt: 489, E(): 1.4e-20, (33.15% identity in 341 aa overlap); O28109|AF2173 (NCD2) from Archaeoglobus fulgidus (274 aa), FASTA scores: opt: 456,E(): 8.9e-19, (36.3% identity in 237 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39348363935903+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3583|Mb3583
MRLRTPLTELIGIEHPVVQTGMGWVAGARLVSATANAGGLGILASATMTLDELAAAITKVKAVTDKPFGVNIRADAADAGDRVELMIREGVRVASFALAPKQQLIARLKEAGAVVIPSIGAAKHARKVAAWGADAMIVQGGEGGGHTGPVATTLLLPSVLDAVAGTGIPVIAAGGFFDGRGLAAALCYGAAGVAMGTRFLLTSDSTVPDAVKRRYLQAGLDGTVVTTRVDGMPHRVLRTELVEKLESGSRARGFAAALRNAGKFRRMSQMTWRSMIRDGLTMRHGKELTWSQVLMAANTPMLLKAGLVDGNTEAGVLASGQVAGILDDLPSCKELIESIVLDAITHLQTASALVE
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