Gene Mb3584
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE ELECTRON TRANSFER PROTEIN FDXB |
| Comments | Mb3584, fdxB, len: 685 aa. Equivalent to Rv3554,len: 685 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 685 aa overlap). Possible fdxB,two-domain protein, with ferredoxin reductase electron transfer component in C-terminal part (EC 1.-.-.-) and unknown function in N-terminal part. Indeed, N-terminal end is similar to O85832 HYPOTHETICAL 36.1 KDA PROTEIN from Sphingomonas aromaticivorans strain F199 (catabolic plasmid pNL1) (309 aa), FASTA scores: opt: 615, E(): 2.5e-30, (33.1% identity in 311 aa overlap); and P73428|SLL1468 HYPOTHETICAL 36.2 KDA PROTEIN from Synechocystis sp. strain PCC 6803 (312 aa), FASTA scores: opt: 317, E(): 4.5e-12, (30.2% identity in 268 aa overlap). And C-terminal end is similar to Q9F9U6|PAAE protein involved in aerobic phenylacetate metabolism from Azoarcus evansii (360 aa), FASTA scores: opt: 935, E(): 7e-50, (43.85% identity in 351 aa overlap); CAC44653|PAAE|SCBAC17A6.08 PUTATIVE PHENYLACETIC ACID DEGRADATION NADH OXIDOREDUCTASE from Streptomyces coelicolor (368 aa), FASTA scores: opt: 93, E(): 9.5e-50,(41.95% identity in 372 aa overlap); Q9FA57|PACI FERREDOXIN from Azoarcus evansii (360 aa), FASTA scores: opt: 925, E(): 2.9e-49, (43.3% identity in 351 aa overlap); P76081|PAAE_ECOLI|B1392 PROBABLE PHENYLACETIC ACID DEGRADATION NADH OXIDOREDUCTASE from Escherichia coli strains K12 and W (356 aa), FASTA scores: opt: 910, E(): 2.4e-48, (43.05% identity in 353 aa overlap); Q9APJ6|PAAE ELECTRON TRANSFER PROTEIN (FRAGMENT) from Hyphomicrobium chloromethanicum (241 aa), FASTA scores: opt: 404, E(): 1.7e-17, (35.45% identity in 234 aa overlap); BAB51608|MLL5100 FERREDOXIN from Rhizobium loti (Mesorhizobium loti) (365 aa), FASTA scores: opt: 316,E(): 5.8e-12, (28.95% identity in 349 aa overlap); etc. C-terminus also similar to P96853|Rv3571|MTCY06G11.18 PUTATIVE ELECTRON TRANSFER PROTEIN from Mycobacterium tuberculosis (358 aa), FASTA scores: opt: 450, E(): 3.6e-20, (32.95% identity in 358 aa overlap). Contains PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. BELONGS TO THE 2FE2S PLANT-TYPE FERREDOXIN FAMILY. COFACTOR: BINDS A 2FE-2S CLUSTER (BY SIMILARITY). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3935900 | 3937957 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3584|fdxB
MTDACQAEYAIAAMSTVEMDQAAPESAAHHPLPDPGESVPRLALPTIGIFLATLTAFVGSTTAYISGWIPFWVTIPVNAAVTFVMFTVVHDASHYAISSIRWVNGLFGRLAWLFVGPVVAFPAFGYIHIQHHRHSNDDEQDPDTFASHGSLWVLPLRWSMVEYFYIKYYLPRGRSRPVIEVAETLVMMTLFLTGLIVAIVTGNFWTLAIVFLIPQRIGLTVLAWWFDWLPHHGLEDTQRSNRYRATRNRVGAEWLFTPVLLSQNYHLVHHLHPSVPFYRYLRTWRRNEEAYLERNAAISTVFGQQLNPDEYRQWKELNGRLARLLPVRMPARSSSPHAVLHRIPVASVDPITADATLVTFAVPEALRDAFRFEPGQHVTVRTDLGGQGIRRNYSICAPATRAQLRIAVKHIPGGAFSTFVANELKAGDVLELMTPTGRFGTPLDPLHRKHYVGLVAGSGITPVLSILATTLEIETESRFTLIYGNRTKESTMFRAELDRLESRYADRLEILHVLSSEPLHTPELRGRIDRDKLTRWLTSTLRPAGVDEWFICGPLAMATAVRETLIEHGVDSERIHLELFYGFDTPPATRPSYAGATVTFTLSGQRAIFDLVPGDSILEGALGLRSDAPYACMGGACGTCRAKLIEGNVEMDHNFALRKAELDAGYILTCQSHPTTPFVAVDYDA
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