Gene Mb3591
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE FATTY-ACID-COA LIGASE FADD3 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) |
| Comments | Mb3591, fadD3, len: 507 aa. Equivalent to Rv3561,len: 507 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 507 aa overlap). Probable fadD3,fatty-acid-CoA synthetase (EC 6.2.1.-), similar to many substrate-CoA symthetases/ligases e.g. Q9KBC2|BH2006 LONG-CHAIN ACYL-COA SYNTHETASE from Bacillus halodurans (513 aa), FASTA scores: opt: 821, E(): 1.6e-43, (32.9% identity in 517 aa overlap); Q9EY88|FCS FERULOYL-COA SYNTHETASE from Amycolatopsis sp. HR167 (491 aa) FASTA scores: opt: 767, E(): 3.5e-40, (37.65% identity in 502 aa overlap); Q9ZIP5|MATB MALONYL CoA SYNTHETASE from Rhizobium leguminosarum (504 aa), FASTA scores: opt: 758,E(): 1.3e-39, (33.7% identity in 472 aa overlap); Q9CD27|FADD2|ML2546 ACYL-COA SYNTHASE from Mycobacterium leprae (548 aa), FASTA scores: opt: 700, E(): 5.6e-36,(31.85% identity in 515 aa overlap); P29212|LCFA_ECOLI|FADD|OLDD|B1805 LONG-CHAIN-FATTY-ACID--COA LIGASE from Escherichia coli strain K12 (561 aa), FASTA scores: opt: 532, E(): 6.3e-28,(30.0% identity in 533 aa overlap); etc. Also similar to other from Mycobacterium tuberculosis eg O53306|FADD13|Rv3089|MTV013.10 (503 aa), FASTA scores: opt: 819, E(): 2.1e-43, (35.1% identity in 490 aa overlap). Contains PS00455 Putative AMP-binding domain signature. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3944852 | 3946375 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3591|fadD3
MINDLRTVPAALDRLVRQLPDHTALIAEDRRFTSTELRDAVYGAAAALIALGVEPADRVAIWSPNTWHWVVACLAIHHAGAAVVPLNTRYTATEATDILDRAGAPVLFAAGLFLGADRAAGLDRAALPALRHVVRVPVEADDGTWDEFIATGAGALDAVAARAAAVAPQDVSDILFTSGTTGRSKGVLCAHRQSLSASASWAANGKITSDDRYLCINPFFHNFGYKAGILACLQTGATLIPHVTFDPLHALRAIERHRITVLPGPPTIYQSLLDHPARKDFDLSSLRFAVTGAATVPVVLVERMQSELDIDIVLTAYGLTEANGMGTMCRPEDDAVTVATTCGRPFADFELRIADDGEVLLRGPNVMVGYLDDTEATAAAIDADGWLHTGDIGAVDQAGNLRINDRLKDMYICGGFNVYPAEVEQVLARMDGVADAAVIGVPDQRLGEVGRAFVVARPGTGLDEASVIAYTREHLANFKTPRSVRFVDVLPRNAAGKVSKPQLRELG
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