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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ACYL-COA DEHYDROGENASE FADE33
CommentsMb3594, fadE33, len: 318 aa. Equivalent to Rv3564,len: 318 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 318 aa overlap). Probable fadE33,acyl-CoA dehydrogenase (EC 1.3.99.-), similar to others e.g. Q9A5G8|CC2479 from Caulobacter crescentus (344 aa),FASTA scores: opt: 373, E(): 1.9e-15, (34.3% identity in 338 aa overlap); Q9I4V4|PA1020 from Pseudomonas aeruginosa (370 aa), FASTA scores: opt: 277, E(): 1.4e-09, (31.95% identity in 335 aa overlap); Q9X7Y6|SC6A5.40c from Streptomyces coelicolor (395 aa), FASTA scores: opt: 273,E(): 2.5e-09, (30.1% identity in 352 aa overlap); P45857|ACDB_BACSU|MMGC from Bacillus subtilis (379 aa),FASTA scores: opt: 478, E(): 7.9e-22, (32.9% identity in 292 aa overlap); etc. Also similar to others from Mycobacterium tuberculosis e.g. P96845|FADE32|Rv3563|MTCY06G11.10 (319 aa), FASTA scores: opt: 478, E(): 7.9e-22, (32.9% identity in 292 aa overlap). COULD BELONG TO THE ACYL-COA DEHYDROGENASES FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS39484623949418+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3594|fadE33
MTPPEERQMLRETVASLVAKHAGPAAVRAAMASDRGYDESLWRLLCEQVGAAALVIPEELGGAGGELADAAIVVQELGRALVPSPLLGTTLAELALLAAAKPDAQALTELAQGSAIGALVLDPDYVVNGDIADIVVAATSGQLTRWTRFSAQPVATMDPTRRLARLQSEETEPLCPDPGIADTAAILLAAEQIGAAERCLQLTVEYAKSRVQFGRPIGSFQALKHRMADLYVTIAAARAVVADACHAPTPTNAATARLAASEALSTAAAEGIQLHGGIAITWEHDMHLYFKRAHGSAQLLESPREVLRRLESEVWESP
      
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