Gene Mb3624
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE CONSERVED LIPOPROTEIN LPQF |
| Comments | Mb3624, lpqF, len: 452 aa. Equivalent to Rv3593,len: 452 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 452 aa overlap). Probable lpqF,conserved lipoprotein, equivalent to Q9CBI7|MPQF|ML1923 PROBALE SECRETED PROTEIN from Mycobacterium leprae (454 aa), FASTA scores: opt: 2465, E(): 5.7e-144, (79.15% identity in 451 aa overlap). Also similar to Q9KJ91 HYPOTHETICAL 47.1 KDA PROTEIN from Streptomyces clavuligerus (430 aa), FASTA scores: opt: 609, E(): 5.2e-30, (30.3% identity in 350 aa overlap); and some similarity with putative beta-lactamases e.g. Q9RYR7|DRA0241 BETA LACTAMASE-RELATED PROTEIN from Deinococcus radiodurans (499 aa), FASTA scores: opt: 322,E(): 2.5e-12, (28.25% identity in 322 aa overlap). Equivalent to AAK48057 from Mycobacterium tuberculosis strain CDC1551 (438 aa) but longer 14 aa. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3977567 | 3978925 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3624|lpqF
MGPARLHNRRAGRRMLALSAAAALIVALASGCSSAPTPSANAANHGHRIDTRTPPGLRAQQTMDMLNSDWPIGEIGVGTLAAPGQVDTVKTTMEALWWDRPFALAGVDIGASVAALHLISSYGAQQDIRIHTDDDGWVDRFDVETQAPSIASWRDVDAVLSKTGARYSFQVAKVDNGRCDPVAGTSTGESLPLASIFKLYVLHALAGAVQHNTVSWDDLLTVTAKSKAVGSSGLELPVGARVSVRTAAEKMIATSDNMATDLLIERLGTRAIEEALASAGHHDPASMTPFPTMYELFSVGWGKPDLRDQWKHATQQVRAQILRQTNSTPYQPDPTRAHTPASNYGAEWYGSAEDICRVHAALRADAVGPASPVRQIMSAVPGIQLDRSVWPYIGAKAGGLPGDLTFSWYAVDKTGQPWVVSFQLNWPRDHGPTVTGWMLQVARQVFALIAPQ
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