Gene Mb3651c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | conserved protein |
| Comments | Mb3651c, -, len: 461 aa. Equivalent to Rv3627c,len: 461 aa, from Mycobacterium tuberculosis strain H37Rv,(99.6% identity in 461 aa overlap). Hypothetical ala-rich protein which may have cleavable signal peptide at N-terminal end. Equivalent to O69539|MLCB2548.20c|ML0211 HYPOTHETICAL 47.2 KDA PROTEIN from Mycobacterium leprae (461 aa), FASTA scores: opt: 2295, E(): 3.5e-116, (76.2% identity in 462 aa overlap); and C-terminal end shows similarity with O05758|MLCB5.28c HYPOTHETICAL 24.1 KDA PROTEIN from Mycobacterium leprae (225 aa), FASTA scores: opt: 268, E(): 1.8e-07, (32.25% identity in 220 aa overlap). Also similar (or with similarity) to various proteins (notably penicillin binding proteins) e.g. Q9X8I8|SCE9.15c HYPOTHETICAL 45.9 KDA PROTEIN from Streptomyces coelicolor (459 aa) FASTA scores: opt: 707,E(): 8.3e-31, (35.75% identity in 439 aa overlap); Q9Z541|SC9B2.18c PUTATIVE CARBOXYPEPTIDASE from Streptomyces coelicolor (451 aa), FASTA scores: opt: 450,E(): 5.3e-17, (31.75% identity in 469 aa overlap); Q9JVV4|NMA0665 PUTATIVE PEPTIDASE from Neisseria meningitidis (serogroup A) (or Q9JY10|NMB1797 from serogroup B) (469 aa), FASTA scores: opt: 269, E(): 3e-07,(26.15% identity in 463 aa overlap); O85665|PBP3 PENICILLIN BINDING PROTEIN 3 from Neisseria gonorrhoeae (469 aa), FASTA scores: opt: 265, E(): 4.9e-07, (31.85% identity in 201 aa overlap); P45161|PBP4_HAEIN|DACB|HI1330 PENICILLIN-BINDING PROTEIN 4 PRECURSOR/PEPTIDASE (479 aa) FASTA scores: opt: 230, E(): 3.8e-05, (27.9% identity in 394 aa overlap); P24228|PBP4_ECOLI|DACB|B3182 PENICILLIN-BINDING PROTEIN 4 PRECURSOR from Escherichia coli strain K12 (477 aa), FASTA scores: opt: 166, E(): 0.1, (28.2% identity in 408 aa overlap); etc. |
| Functional category | Conserved hypotheticals |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4003137 | 4004522 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3651c|Mb3651c
MGPTRWRKSTHVVVGAAVLAFVAVVVAAAALVTTGGHRAGVRAPVPPPRPPTVKAGVVPVADTAATPSAAGVTAALAVVAVDPDLGKLAGRITDALTGQELWQRLDDVPLVPASTNKILTAAAALLTLDRQARISTRVVAGGQNPQGPVVLVGAGDPTLSAAPPGQDTWYHGAARIGDLVEQIRRSGVTPTAVQVDASAFSGPTMAPGWDPADIDNGDIAPIEAAMIDAGRIQPTTVNSRRSRTPALDAGRELAKALGLDPAAVTIASAPAGARQLAVVQSAPLIQRLSQMMNASDNVMAECIGREVAVAINRPQSFSGAVDAVTSRLNTAHIDTAGAALVDSSGLSLDNRLTARTLDATMQAAAGPDQPALRPLLDLLPIAGGSGTLGERFLDAATDQGPAGWLRAKTGSLTAINSLVGVLTDRSGRVLTFAFISNEAGPNGRNAMDALATKLWFCGCTT
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