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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
CommentsMb3653c, -, len: 365 aa. Equivalent to Rv3629c,len: 365 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 365 aa overlap). Probable conserved integral membrane protein, equivalent to O69543|MLCB2548.26|ML0205 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (356 aa), FASTA scores: opt: 1547,E(): 3e-89, (66.2% identity in 361 aa overlap). Also similar to other membrane and hypothetical proteins e.g. CAC37534|SCIF3.15c PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (363 aa), FASTA scores: opt: 819,E(): 7.7e-44, (51.55% identity in 351 aa overlap); Q9CGK3|YKJK HYPOTHETICAL PROTEIN from Lactococcus lactis (subsp. lactis) (Streptococcus lactis) (339 aa) FASTA scores: opt: 683, E(): 2.2e-35, (48.3% identity in 350 aa overlap); Q9KY24|SCC8A.24c PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (380 aa) FASTA scores: opt: 528, E(): 1.1e-25, (50.25% identity in 372 aa overlap); Q9RJH8|SCF73.09 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (370 aa) FASTA scores: opt: 439, E(): 3.9e-20, (50.2% identity in 384 aa overlap); Q9PE36|XF1192 INTEGRAL MEMBRANE PROTEIN from Xylella fastidiosa (341 aa), FASTA scores: opt: 337, E(): 8.3e-14, (47.65% identity in 361 aa overlap); etc.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40051944006291-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3653c|Mb3653c
MSTFRIFGFSLLMTVVALVTGYLHGGPTALFLLAVLALLEVSLSFDNAIINAAILQRMSPFWQRMFLTIGILIAVFGMRLVFPLAIIWTTAGLDPVRAMELALRPPAHGALEFADGSPSYEKLITAAHPQIAAFGGMFLLMLFLDFVVHDRDIKWLKWIEVPFARIGRLGQVPVIVASVGLVLAGALLTHSSDQRGTVLIAGLLGMVTYLVVNGISRAFRPAGLGEATPGVQARQAAGKAGCALFLYLEVLDAAFSFDGVTGAFAITTDPIIIALGLGVVGAMFVRSITIYLVRQDTLDRYVYLEHGAHWAIGALAIILLLSIDHRFAVPEWVTASVGVVFIGAAFTESVRRNRLTVRSPTKFGS
      
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