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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible transposase
CommentsMb3662, -, len: 248 aa. Equivalent to Rv3638, len: 248 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 248 aa overlap). Possible transposase,highly similar to Q9RLQ8|ISTB ISTB PROTEIN from Mycobacterium bovis (266 aa), FASTA scores: opt: 784, E(): 4e-46, (78.0% identity in 259 aa overlap); and similar to others e.g. P15026|ISTB_PSEAE INSERTION SEQUENCE IS21 PUTATIVE ATP-BINDING PROTEIN from Pseudomonas aeruginosa (265 aa), FASTA scores: opt: 420, E(): 2.2e-21, (38.8% identity in 255 aa overlap); Q45619|ISTB_BACST INSERTION SEQUENCE IS5376 PUTATIVE ATP-BINDING PROTEIN from Bacillus stearothermophilus (251 aa), FASTA scores: opt: 402, E(): 3.6e-20, (34.5% identity in 232 aa overlap); P15026|ISTB_ECOLI ISTB PROTEIN from Escherichia coli (265 aa), FASTA scores: opt: 419, E(): 8e-23, (38.8% identity in 255 aa overlap); etc. C-terminus highly similar to C-terminus of P96287|Rv2944|MTCY24G1.05 HYPOTHETICAL 25.5 KDA PROTEIN from Mycobacterium tuberculosis strain H37Rv (alias AAK47343|MT3016 IS1533, ORFB from Mycobacterium tuberculosis strain CDC1551) (238 aa), FASTA scores: opt: 784, E(): 3.6e-46, (87.4% identity in 135 aa overlap).
Functional categoryInsertion seqs and phages
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40142214014967+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3662|Mb3662
MAAKTATNSRDVAAELAYLTRALKAPTLRGAIEQLADRARTKTWSYEEFLAACLQREVSARESHGGEGRIRAARFPSRKSLEEFDFDHARGLKRDTIAHLGTLDFVTLAIGIAIRACQAGHRVLFATASQWVDRLAAAHHSGTLQSELIRLARYPLLVVDEVGYIPFEPEAANLFFQLVSSRYERASLIVTSNKPFGRWGEVFGDDVVAAAMIDRLVHHAEVIALKGDSYRIKDRDLGRVPTVTADDQ
      
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