Gene Mb3673
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable helicase |
| Comments | Mb3673, -, len: 771 aa. Equivalent to Rv3649, len: 771 aa, from Mycobacterium tuberculosis strain H37Rv,(99.9% identity in 771 aa overlap). Probable helicase (EC 3.6.-.-), similar to many (known or hypothetical) ATP-dependent helicases e.g. Q9X915|SCH5.13 PUTATIVE HELICASE from Streptomyces coelicolor (815 aa) FASTA scores: opt: 2550, E(): 9.6e-139, (52.45% identity in 774 aa overlap); Q05549|YDR291W|D9819.1 PROTEIN SIMILAR TO SEVERAL DNA HELICASES from Saccharomyces cerevisiae (Baker's yeast) (1077 aa), FASTA scores: opt: 1161, E(): 5.9e-59, (31.05% identity in 780 aa overlap); P50830|YPRA_BACSU HYPOTHETICAL HELICASE from Bacillus subtilis (749 aa), FASTA scores: opt: 1154, E(): 1.1e-58,(34.05% identity in 734 aa overlap); Q9KC10|BH1764 ATP-DEPENDENT RNA HELICASE from Bacillus halodurans (764 aa), FASTA scores: opt: 1122, E(): 8e-57, (32.3% identity in 759 aa overlap); etc. SEEMS SIMILAR TO DEAD/DEAH BOX HELICASE FAMILY, AND TO HELICASE C-TERMINAL DOMAIN. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4026018 | 4028333 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3673|Mb3673
MASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPWSHQAEAAELAYAGRHVVIGTGPASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQLRAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWLFSNPEMTHLSVLRNHARWAVLLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAADLIGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGAQTLTFVRSRRAAELTALGARARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLIARDDPLDTYLVHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGLLRRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYLHQGETYVVDSLDFQDGIAFVHAEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTVTNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITSDALVRSGIEATRIPGSLHAAEHAAIGLLPLVASCDRGDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGATAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP
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