Gene Mb3676 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namePE_PGRS60
Gene length315 bp
IdentifierMb3676
Location 4030869 bp
Protein summary information
Molecular mass10636.2 Da
Isoelectric point11.4611
Protein length104 amino acids
Orthologs
M. tuberculosis H37RvRv3652
Cross-references
InterProIPR000084
UniProtKB/TrEMBLQ7TW11
SWISS-MODELA0A1R3Y4T4
General annotation
TypeCDS
FunctionUnknown
Productpe-pgrs family-related protein pe_pgrs60
CommentsMb3676, PE_PGRS60, len: 104 aa. Equivalent to Rv3652, len: 104 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 104 aa overlap). Member of the Mycobacterium tuberculosis PE family, PGRS subfamily of gly-rich proteins, similar at N-terminal end with many e.g. P56877|Y278_MYCTU|Rv0278c|MTV035.06c (957 aa) FASTA scores: opt: 242, E(): 3e-09, (77.35% identity in 53 aa overlap). Originally annotated as the first part of a PE-PGRS family protein (Rv3653/PE_PGRS61 being the second part) but more similar to a PE family protein. Length extended since first submission (+50 aa).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40308694031183+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3676|PE_PGRS60
MSYVIAAPEALVAAATDLATLGSTIGAANAAAAGSTTALLTAGADEVSAAIAAYSECTARPIRHSVRGRRRSMSGSCRPWPQVGAPMRPPRPPASRRCRARSIC
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