Gene Mb3685 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3685
Gene length864 bp
IdentifierMb3685
Location 4036994 bp
Protein summary information
Molecular mass30721.2 Da
Isoelectric point7.9922
Protein length287 amino acids
Orthologues
M. tuberculosisRv3661
Cross-references
InterProIPR006383, IPR006385, IPR023214
UniProtKB/TrEMBLQ7TW02
SWISS-MODELA0A1R3Y4U1
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb3685, -, len: 287 aa. Equivalent to Rv3661, len: 287 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 287 aa overlap). Conserved hypothetical protein, highly similar to O33611|IMD_STRCN from Streptomyces cyaneus (Streptomyces curacoi) protein involved in inhibition of morphological differentiation in Streptomyces azureus (BELONGS TO THE SERB FAMILY) (277 aa) FASTA scores: opt: 1073, E(): 3.5e-61, (61.45% identity in 262 aa overlap); and Q9X923|SCH5.21 PUTATIVE MORPHOLOGICAL DIFFERENTIATION-ASSOCIATED PROTEIN from Streptomyces coelicolor (268 aa), FASTA scores: opt: 1057, E(): 3.6e-60, (61.45% identity in 262 aa overlap). Also similar to various bacterial proteins (principally serB-related proteins) e.g. Q49823|ML2424 HYPOTHETICAL SERB PROTEIN from Mycobacterium leprae (300 aa), FASTA scores: opt: 452, E(): 1.4e-21, (35.8% identity in 257 aa overlap); Q9WX12|SCE68.20 HYPOTHETICAL 32.0 KDA PROTEIN from Streptomyces coelicolor (298 aa), FASTA scores: opt: 415,E(): 3.1e-19, (33.55% identity in 280 aa overlap); Q9RIT2|SERB PHOSPHOSERINE PHOSPHATASE (FRAGMENT) from Streptomyces coelicolor (266 aa), FASTA scores: opt: 405,E(): 1.2e-18, (34.1% identity in 261 aa overlap); etc. Also similar to Q11169|Y505_MYCTU|Rv0505c|MTCY20G9.32c HYPOTHETICAL 39.5 KDA PROTEIN from Mycobacterium tuberculosis (373 aa), FASTA scores: opt: 454, E(): 1.2e-21, (35.15% identity in 276 aa overlap). BELONGS TO THE SERB FAMILY.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40369944037857+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3685|Mb3685
MTVSDSPAQRQTPPQTPGGTAPRARTAAFFDLDKTIIAKPSTLAFSKPFFAQGLLNRRAVLKSSYAQFIFLLSGADHDQMDRMRTHLTNMCAGWDVAQVRSIVNETLHDIVTPLVFAEAADLIAAHKLCGRDVVVVSASGEEIVGPIARALGATHAMATRMIVEDGKYTGEVAFYCYGEGKAQAIRELAASEGYPLEHCYAYSDSITDLPMLEAVGHASVVNPDRGLRKEASVRGWPVLSFSRPVSLRDRIPAPSAAAIATTAAVGISALAAGAVTYALLRRFAFQP
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