Gene Mb3697c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN) |
| Comments | Mb3697c, -, len: 227 aa. Equivalent to Rv3673c,len: 227 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 227 aa overlap). Possible membrane protein, thioredoxin-like protein (thiol-disulfide interchange protein) (EC 1.-.-.-), equivalent to Q9CB93|ML2300 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (215 aa), FASTA scores: opt: 978, E(): 2.5e-52,(71.15% identity in 215 aa overlap). Some similarity with thioredoxin-related proteins e.g. P35160|RESA_BACSU RESA PROTEIN from Bacillus subtilis (181 aa), FASTA scores: opt: 212, E(): 5.7e-06, (30.55% identity in 108 aa overlap); Q9RXW6|DR0189 THIOL:DISULFIDE INTERCHANGE PROTEIN from Deinococcus radiodurans (185 aa) FASTA scores: opt: 206, E(): 1.3e-05, (33.8% identity in 139 aa overlap); Q9I505|PA0953 PROBABLE THIOREDOXIN from Pseudomonas aeruginosa (154 aa), FASTA scores: opt: 180,E(): 0.00044, (34.85% identity in 109 aa overlap); Q9KCP7|BH1522 THIOREDOXIN (THIOL:DISULFIDE INTERCHANGE PROTEIN) from Bacillus halodurans (177 aa), FASTA scores: opt: 178, E(): 0.00064, (31.75% identity in 107 aa overlap); P43221|TLPA_BRAJA THIOL:DISULFIDE INTERCHANGE PROTEIN (CYTOCHROME C BIOGENESIS PROTEIN) from Bradyrhizobium japonicum (221 aa), FASTA scores: opt: 189,E(): 0.00017, (26.85% identity in 227 aa overlap); etc. Also similar to O06392|Rv0526|MTCY25D10.05 HYPOTHETICAL 23.2 KDA PROTEIN from Mycobacterium tuberculosis (216 aa) FASTA scores: opt: 160, E(): 0.0093, (27.45% identity in 142 aa overlap). Contains PS00194 Thioredoxin family active site. POSSIBLY BELONGS TO THE THIOREDOXIN FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4051821 | 4052504 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3697c|Mb3697c
MPSLPTTPAETAMTTLTGKTRWTIAILAVVAALMAALVAQLHDYSASSTISQRPAPREHRDGDTPEALAWSRQRANLPPCPAAGNGPGAAALRGVVVVCAGDGSAVDVARALAGRRVVINLWAHWCAPCMTELPVMAEYQRRVGPAVLVVTVHQGQNEAAALSRLADLGVRLPTLQDDRRRVAAALRVANVMPATVVLRPDGSVAQTLPRAFGSADEIVAAVGNDAG
Bibliography
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