Gene Mb3720 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3720
Gene length933 bp
IdentifierMb3720
Location 4074553 bp
Protein summary information
Molecular mass33167.9 Da
Isoelectric point9.1691
Protein length310 amino acids
Orthologues
M. tuberculosisRv3695
Cross-references
InterProIPR010432
UniProtKB/TrEMBLQ7TVX0
SWISS-MODELA0A1R3Y501
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE CONSERVED MEMBRANE PROTEIN
CommentsMb3720, -, len: 310 aa. Equivalent to Rv3695, len: 310 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 310 aa overlap). Possible conserved membrane protein, equivalent, but longer 88 aa, to Q9CB83|ML2312 POSSIBLE MEMBRANE PROTEIN from Mycobacterium leprae (196 aa), FASTA scores: opt: 898, E(): 5.2e-36,(71.05% identity in 190 aa overlap). Also highly similar to Q9KZM3|SCE34.02 PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (318 aa), FASTA scores: opt: 740,E(): 2.4e-28, (43.25% identity in 319 aa overlap); and similar to P72718|SLR0254 HYPOTHETICAL 30.4 KDA PROTEIN from Synechocystis sp. strain PCC 6803 (266 aa), FASTA scores: opt: 287, E(): 6.1e-07, (29.6% identity in 260 aa overlap); Q9HW83|PA4318 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (265 aa), FASTA scores: opt: 250,E(): 3.5e-05, (32.0% identity in 203 aa overlap); Q9KEW5|BH0734 HYPOTHETICAL PROTEIN from Bacillus halodurans (266 aa), FASTA scores: opt: 168, E(): 0.0047,(25.95% identity in 231 aa overlap); etc. C-terminal end shows some similarity to proline-rich proteins e.g. Q62106 PROLINE-RICH SALIVARY PROTEIN (FRAGMENT) from Mus musculus (Mouse) (188 aa) (36.1% identity in 97 aa overlap). Equivalent to AAK48164 from Mycobacterium tuberculosis strain CDC1551 (269 aa) but longer 41 aa.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40745534075485+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3720|Mb3720
MSEVVTGDAVVLDVQIAQLPVRAVSAVIDITIIFIGYILGLMLWATALTQFDEALTTAFLIIFTVLALVGYPLVWETATRGRSVGKIVMGLRVVSDDGGPERFRQALFRALASVVEIWMLLGSPAVICSMLSPKAKRVGDVFAGTVVVSERGPRLGPPPVMPPSLAWWASSLQLSGLTAGQAEVARQFLVRAPQLDPALREQMAYRIAGDVVARIAPPPPPGVPPQLVLAAVLAERHRRELLRLRPTLPPAGQAPWAQMAPHRGWPPGLSGATPWSPQQPVIPWPEPDPPPQAAPWPQQAPDGPGFSPPG
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