Gene Mb3739 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3739
Gene length1242 bp
IdentifierMb3739
Location 4094441 bp
Protein summary information
Molecular mass43424.4 Da
Isoelectric point6.7414
Protein length413 amino acids
Orthologs
M. tuberculosis H37RvRv3712
M. tuberculosis MTBC0mtbc0_003935
Cross-references
InterProIPR013221, IPR013564
UniProtKB/TrEMBLQ7TVV4
SWISS-MODELA0A1R3Y514
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE LIGASE
CommentsMb3739, -, len: 413 aa. Equivalent to Rv3712, len: 413 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 413 aa overlap). Possible ligase (EC 6.-.-.-), equivalent to O69522|ML2326|MLCB2407.24c HYPOTHETICAL 43.8 KDA PROTEIN (POSSIBLE LIGASE) from Mycobacterium leprae (411 aa), FASTA scores: opt: 2265,E(): 8e-129, (84.25% identity in 413 aa overlap). Also similar to ligases or hypothetical proteins e.g. Q9FCA1|2SCG58.12 PUTATIVE LIGASE from Streptomyces coelicolor (412 aa), FASTA scores: opt: 1168, E(): 6.7e-63, (45.8% identity in 406 aa overlap); P74303|SLR0938 HYPOTHETICAL 50.2 KDA PROTEIN from Synechocystis sp. strain PCC 6803 (459 aa), FASTA scores: opt: 392, E(): 3.1e-16, (28.45% identity in 397 aa overlap); Q99ZX1|SPY1035 PUTATIVE UDP-N-ACETYLMURAMYL TRIPEPTIDE SYNTHETASE (EC 6.3.2.13) from Streptococcus pyogenes (445 aa), FASTA scores: opt: 335, E(): 8.1e-13,(29.2% identity in 438 aa overlap); Q9CGJ0|YLBD HYPOTHETICAL PROTEIN from Lactococcus lactis (subsp. lactis) (Streptococcus lactis) (449 aa), FASTA scores: opt: 324, E(): 3.8e-12, (28.75% identity in 445 aa overlap); Q9ZGG7|MURC UDP-N-ACETYLMURAMYL TRIPEPTIDE SYNTHETASE from Heliobacillus mobilis (455 aa), FASTA scores: opt: 292, E(): 3.2e-10, (30.75% identity in 449 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS40944414095682+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3739|Mb3739
MVTTRARLALAAGAGARWASRVTGRGAGAMIGGLVAMTLDRSILRQLGMGRRTVVVTGTNGKSTTTRMTAAALGTLGAVATNAEGANMDAGLVAALAAHRDAELAVLEVDEMHVPHISDAVDPAVVVLLNLSRDQLDRVGEINVIERTLRAGLARHPDAVVVANCDDVLMTSAAYDSPNVVWVAAGGAWSNDSVSCPRSSEVIVRKAPSQEDHWYSTGADFKRPAPHWWFDDATLYGPDGLALPMRLALPGSVNRGNAAQAVAAAVALGADPAVAVAAVCQVDEVAGRYRTVRIGAHQARILLAKNPAGWQEALAMVDKHADGVVIAVNGRVPDGEDLSWLWDVRFEHFETTRVVAAGERGTDLAVRLGYAGVEHTLVHDTVAAIASCPPGRVEVVANYTAFLQLQRALARRG
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