Gene Mb3752
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | possible oxidoreductase |
| Comments | Mb3752, -, len: 333 aa. Equivalent to Rv3725, len: 309 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 250 aa overlap). Possible reductase (EC 1.-.-.-), similar to various oxidoreductases and hypothetical proteins e.g. O34285|HPNA HPNA PROTEIN from Zymomonas mobilis (337 aa), FASTA scores: opt: 317, E(): 6.1e-11, (30.5% identity in 272 aa overlap); Q9SZB3|F17M5.120|AT4G33360|AAK49584 HYPOTHETICAL 37.9 KDA PROTEIN from Arabidopsis thaliana (Mouse-ear cress) (344 aa), FASTA scores: opt: 314, E(): 9.1e-11, (30.35% identity in 267 aa overlap); AAK59445|AT4G33360 PUTATIVE DIHYDROKAEMPFEROL 4-REDUCTASE from Arabidopsis thaliana (Mouse-ear cress) (332 aa), FASTA scores: opt: 313, E(): 1e-10, (30.8% identity in 263 aa overlap); Q9FSC6|CCR CINNAMOYL-COA REDUCTASE (EC 1.2.1.44) from Populus trichocarpa (Western balsam poplar) (338 aa), FASTA scores: opt: 305, E(): 2.9e-10, (30.3% identity in 274 aa overlap); Q9M631 CINNAMOYL CoA REDUCTASE from Populus tremuloides (Quaking aspen) (337 aa), FASTA scores: opt: 291, E(): 1.8e-09, (30.15% identity in 272 aa overlap); P73212|DFRA_SYNY3|LR1706 PUTATIVE DIHYDROFLAVONOL-4-REDUCTASE (EC 1.1.1.219) (DIHYDROKAEMPFEROL 4-REDUCTASE) from Synechocystis sp. strain PCC 6803 (343 aa), FASTA scores: opt: 278, E(): 1e-08, (29.35% identity in 259 aa overlap); etc. Also some similarity to proteins from Mycobacterium tuberculosis e.g. P96816|Rv0139|MTCI5.13 HYPOTHETICAL PROTEIN (340 aa) FASTA scores: opt: 234, E(): 3.2e-06, (28.25% identity in 269 aa overlap); and O06373|galE1|Rv3634c|MTCY15C10.18 PROBABLE UDP-GLUCOSE 4-EPIMERASE (314 aa) (27.3% identity in 194 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a single base insertion (*-a) leads to a longer product with a different COOH part compared to its homolog in Mycobacterium tuberculosis (333 aa versus 309 aa). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4107673 | 4108674 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3752|Mb3752
MQNATMRVLVTGGTGFVGGWTAKAIADAGHSVRFLVRNPARLKTSVAKLGVDVSDFAVADISDRDSVREALNGCDAVVHSAALVATDPRETSRMLSTNMAGAQNVLGQAVELGMDPIVHVSSFTALFRPNLATLSADLPVAGGTDGYGQSKAQIEIYARGLQDAGAPVNITYPGMVLGPPVGDQFGEAGEGVRSALWMHVIPGRGAAWLIVDVRDVAALHAALLESGRGPRRYTAGGHRIPVPELAKILGEVAGTTMLAVPVPDSALRVAGSVLDQAGPYLPFNTPFTAAGMQYYTQMPEPDDSPSEKELGITYRDPRDTVADTVTALRGLGS
Bibliography
No article yet recorded
