Gene Mb3754
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE OXIDOREDUCTASE |
| Comments | Mb3754, -, len: 602 aa. Equivalent to Rv3727, len: 602 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 602 aa overlap). Possible oxidoreductase (EC 1.-.-.-), similar to several plants phytoene dehydrogenases/desaturases (EC 1.3.-.-) e.g. Q9HSE1|CRTI3|VNG0277G PHYTOENE DEHYDROGENASE from Halobacterium sp. strain NRC-1 (541 aa), FASTA scores: opt: 299, E(): 1.1e-10, (29.85% identity in 576 aa overlap); Q9FZL6|CITPDS1 PHYTOENE DESATURASE from Citrus unshiu (Satsuma orange) (553 aa), FASTA scores: opt: 164,E(): 0.018, (24.2% identity in 434 aa overlap); Q07356|CRTI_ARATH|PDS|AT4G14210|DL3145c PHYTOENE DEHYDROGENASE PRECURSOR from Arabidopsis thaliana (Mouse-ear cress) (566 aa), FASTA scores: opt: 163, E(): 0.021, (23.95% identity in 434 aa overlap); etc. N-terminal end similar to O69871|SC1C3.29 PUTATIVE PROTOPORPHYRINOGEN OXIDASE (FRAGMENT) from Streptomyces coelicolor (61 aa), FASTA scores: opt: 154, E(): 0.012,(60.45% identity in 43 aa overlap). The region between aa 155-310 is highly similar to Q49778|B2126_C1_169 from Mycobacterium leprae (159 aa), FASTA scores: opt: 437,E(): 1.5e-19, (46.6% identity in 161 aa overlap). And the region between aa 462-546 is highly similar to the N-terminal end of Q50003|U1764T from Mycobacterium leprae (155 aa), FASTA scores: opt: 277, E(): 8.3e-10, (57.65% identity in 85 aa overlap). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4110415 | 4112223 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3754|Mb3754
MKPSPADTHVVIAGAGIAGLAAAMILAEAGVRVTLCEAASEAGGKAKSLRLADGHPTEHSLRVYTDTYQTLLTLFSRIPTEHDRTMLDNLVGVSMVSATAQGVIGRIAAPVALQRRRPTFARIIGKVVEPPRQLVRILLRGPMVIVGLAQRGVPATDVLHYLYAHLRLLWMCRERLLAELGDISYADYLQLGCKSAQAQEFFSAVPRIYVAARTSAEAAAIAPIVLKGLFRLKSNCPSALNDAKLPAIMMMDGPTSERMVDPWIRHLTRLGVDIHFNTRVGDLEFDDGRVTALISSDGRRFACDYALLAVPYLTLRELAKSAHVKRYLPQLTQQHALALEASNGIQCFLRDLPATWPPFIRPGVVTTHLQSQWSLVCVLQGEGFWKNVRLPEGTRYVLSITWSDVETPGPVFDRPLSECTPDEILTECLTQCGLDKSNVLGWRIDHELKHLDEAEYEKVASELPPHLVSAPARGQRMVNFSPLTVLMPGARHRSPGICTSVPNLLLAGEVIYSPDLTLFVPTMEKAACSGYLAARQIMNMVASHAAPLRIDFRDPAPFAVLRRVDRWFWSRRRRPPDRSTFATPPTAMPAPSHLTDVDRSAS
Bibliography
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