Gene Mb3763
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARAC/XYLS-FAMILY) |
| Comments | Mb3763, -, len: 353 aa. Equivalent to Rv3736, len: 353 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 353 aa overlap). Probable transcriptional regulator, araC/xylS family, similar to many transcriptional regulators and hypothetical proteins e.g. CAC38740 HYPOTHETICAL 35.4 KDA PROTEIN from Bradyrhizobium japonicum (318 aa), FASTA scores: opt: 438,E(): 2e-20, (29.4% identity in 306 aa overlap); Q9HZ25|PA3215 PROBABLE TRANSCRIPTIONAL REGULATOR from Pseudomonas aeruginosa (337 aa), FASTA scores: opt: 395,E(): 1.1e-17, (30.3% identity in 320 aa overlap); Q9HTN1|PA5324 PROBABLE TRANSCRIPTIONAL REGULATOR from Pseudomonas aeruginosa (356 aa), FASTA scores: opt: 313,E(): 1.8e-12, (25.85% identity in 329 aa overlap); Q9Z3Y6|PHBR TRANSCRIPTIONAL REGULATOR PHBR from Pseudomonas sp. 61-3 (379 aa), FASTA scores: opt: 271,E(): 8.3e-10, (22.95% identity in 357 aa overlap); etc. Also highly similar to Q06861|VIRS_MYCTU|Rv3082c|MTV013.03c POSSIBLE VIRULENCE-REGULATING PROTEIN from Mycobacterium tuberculosis (340 aa), FASTA scores: opt: 656, E(): 3.7e-34, (36.95% identity in 333 aa overlap); and similar to other hypothetical mycobacterial proteins e.g. P71663|YD95_MYCTU|Rv1395|MT1440|MTCY21B4.12 (344 aa). Contains helix-turn-helix motif at aa 245-266 (Score 1140,+3.07 SD). SEEMS BELONG TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL REGULATORS. |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4124094 | 4125155 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3763|Mb3763
MSVVRGTALANYPSLVAGLGGDPATLLRAAGVRDQDVGNYDAFISIRAAIRAIESAAAVTATMDFGRRLAQRQGIEILGPVGVAARTAATVGDALAIFNTFMAAYSPVIAIRITPLAGQRSFIALEFLLDEPASYPQTMELALGVALGVIRLLLGADYAPLAVHLPHDPLTPEAFYLQYFGCRPYFAERVGGFTMRTADLSRPLNRDDVAHRVVVDYLSSITPLGEGIVESVRTIVRQLLPTGAATLNVVAEQFHLHPKTLQRRLAEENTTFVILVDRVRKDVADRYLRTTGIGLTHLARELGYAEQSVLTRSCKRWFGTGPAAYRNQARLQTTVSAPGSGRGPNPGNVSVSC
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