Gene Mb3804
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | probable lipase lipe |
| Comments | Mb3804, lipE, len: 415 aa. Equivalent to Rv3775,len: 415 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 415 aa overlap). Probable lipE,hydrolase lipase (EC 3.1.-.-), equivalent to Q9CD95|LIPE|ML0119 PROBABLE HYDROLASE from Mycobacterium leprae (411 aa), FASTA scores: opt: 2418, E(): 6.4e-144,(84.75% identity in 406 aa overlap). Also similar to other esterases e.g. Q9ABH2|CC0255 ESTERASE A from Caulobacter crescentus (374 aa), FASTA scores: opt: 427, E(): 2.4e-19,(28.9% identity in 391 aa overlap); O87861|ESTA ESTERASE A from Streptomyces chrysomallus (389 aa), FASTA scores: opt: 417, E(): 1e-18, (31.0% identity in 361 aa overlap); Q9RK50|SCF12.08 PUTATIVE ESTERASE from Streptomyces coelicolor (376 aa), FASTA scores: opt: 385, E(): 1e-16,(31.35% identity in 373 aa overlap); etc. Also similar to proteins from Mycobacterium tuberculosis e.g. P71778|Rv1497|MTCY277.19 HYPOTHETICAL 45.8 KDA PROTEIN (429 aa), FASTA scores: opt: 457, E(): 3.5e-21, (30.4% identity in 395 aa overlap). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4155980 | 4157227 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3804|lipE
MRAGDGKIRVPADLDAVTATGEEDHSEIDGAAVDRIWRAARHWYRAGMHPAIQLCIRHHGRVVLNRAIGHGWGNAPTDEADAEKIPVTTDTPFCVYSAAKAITATVVHMLVERGHFALDDRVCEYLPSYTSHGKHRTTIRHVLTHSAGVPFPTGPRPDVRRADDHEYAVERLGELRPLYRPGLVHIYHALTWGPLMREIVYAATGKEIREILATEILDPLGFRWTNFGVAERDVPLVAPSHATGRQLPPVIAAVFRKAIGGTVHEIIPYTNTPFFLSTILPSSNTVSTANELSRFMEILRRGGELDGVRVLSPETLRGAVTECRRLRPDFATGLMPLRWGTGFMLGSAKYGPFGRNAPAAFGHLGLVNIAVWADPERALSGGLISSGKPGRDPEAGRYGALLNAITAEIPRASSG
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