Gene Mb3811 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameglft1
Gene length915 bp
IdentifierMb3811
Location 4164642 bp
Protein summary information
Molecular mass33864.0 Da
Isoelectric point9.2788
Protein length304 amino acids
Orthologs
M. tuberculosis H37RvRv3782
M. tuberculosis MTBC0mtbc0_004010
Cross-references
UniProtKB/TrEMBLQ7TVP0
SWISS-MODELA0A1R3Y572
General annotation
TypeCDS
FunctionUnknown
Productudp-galactofuranosyl transferase glft1
CommentsMb3811, -, len: 304 aa. Equivalent to Rv3782, len: 304 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 304 aa overlap). Possible L-rhamnosyltransferase (EC 2.4.1.-), equivalent to Q9CDA1|RFBE|ML0113 PUTATIVE GLYCOSYL TRANSFERASE from Mycobacterium leprae (283 aa), FASTA scores: opt: 1583,E(): 9.3e-96, (81.6% identity in 277 aa overlap). Also some similarity with AAK68916|WCFN PUTATIVE GLYCOSYLTRANSFERASE from Bacteroides fragilis (291 aa) FASTA scores: opt: 241, E(): 2.1e-08, (30.75% identity in 195 aa overlap); O58161|PH0424 HYPOTHETICAL 40.5 KDA PROTEIN from Pyrococcus horikoshii (348 aa), FASTA scores: opt: 194, E(): 2.8e-05, (23.85% identity in 302 aa overlap); O26448|MTH348 RHAMNOSYL TRANSFERASE from Methanothermobacter thermautotrophicus (313 aa) FASTA scores: opt: 177, E(): 0.00033, (28.2% identity in 333 aa overlap); O07868|CPS19BQ PUTATIVE RHAMNOSYL TRANSFERASE FASTA (300 aa) scores: opt: 156, E(): 0.0074, (25.45% identity in 232 aa overlap); and other putative transferases. Note that C-terminal end shows some similarity with part of Q05161|RFB O-ANTIGEN BIOSYNTHESIS PROTEIN B from Escherichia coli strain 0101. Note that previously known as rfbE.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41646424165556+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3811|glft1
MTESVFAVVVTHRRPDELAKSLDVLTAQTRLPDHLIVVDNDGCGDSPVRELVAGQPIATTYLGSRRNLGGAGGFALGMLHALAQGADWVWLADDDGHAQDARVLATLLACAEKYSLAEVSPMVCNIDDPTRLAFPLRRGLVWRRRASELRTEAGQELLPGIASLFNGALFRASTLAAIGVPDLRLFIRGDEVEMHRRLIRSGLPFGTCLDAAYLHPCGSDEFKPILCGRMHAQYPDDPGKRFFTYRNRGYVLSQPGLRKLLAQEWLRFGWFFLVTRRDPKGLWEWIRLRRLGRREKFGKPGGSA
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