Gene Mb3812
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER RFBD |
| Comments | Mb3812, rfbD, len: 280 aa. Equivalent to Rv3783,len: 280 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 280 aa overlap). Possible rfbD,polysaccharide-transport integral membrane protein ABC transporter (see citation below), involved in O-antigen/lipopolysaccharides (LPS) transport, equivalent to Q9CDA2|ML0112 PUTATIVE ABC TRANSPORTER COMPONENT from Mycobacterium leprae (276 aa), FASTA scores: opt: 1646,E(): 4e-102, (84.3% identity in 280 aa overlap). Also highly similar to Q9PAF1|XF2567 ABC TRANSPORTER PERMEASE PROTEIN from Xylella fastidiosa (267 aa), FASTA scores: opt: 723, E(): 7.6e-41, (41.3% identity in 259 aa overlap); and similar to others e.g. Q56902|RFBD_YEREN O-ANTIGEN EXPORT SYSTEM PERMEASE PROTEIN from Yersinia enterocolitica (259 aa), FASTA scores: opt: 566, E(): 2e-30, (28.05% identity in 264 aa overlap); Q06955|RFBH RFBH PROTEIN (involved in the export of lipopolysaccharide) (alias Q9KVA3|VC0246) LIPOPOLYSACCHARIDE/O-ANTIGEN TRANSPORT PROTEIN from Vibrio cholerae (257 aa), FASTA scores: opt: 358, E(): 1.3e-16,(24.4% identity in 258 aa overlap); Q9HTB8|WZM|PA5451 MEMBRANE SUBUNIT OF A-BAND LPS EFFLUX TRANSPORTER from Pseudomonas aeruginosa (265 aa), FASTA scores: opt: 263,E(): 2.7e-10, (25.45% identity in 263 aa overlap); etc. BELONGS TO THE ABC-2 SUBFAMILY OF INTEGRAL MEMBRANE PROTEINS. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4165553 | 4166395 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3812|rfbD
MTFMDAQASFQTQSRTLARVRGDLVDGFRRHELWLHLGWQDIKQRYRRSVLGPFWITIATGTTAVAMGGLYSKLFRLELSEHLPYVTLGLIVWNLINAAILDGAEVFVANEGLIKQLPAPLSVHVYRLVWRQMIFFAHNIVIYFVIAIIFPKPWSWADLSFLPALALIFLNCVWVSLCFGILATRYRDIGPLLFSVVQLLFFMTPIIWNDETLRRQGAGRWSSIVELNPLLHYLDIVRAPLLGAHQELRHWLVVLVLTVVGWMLAAFAMRQYRARVPYWV
Bibliography
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