Gene Mb3819 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namedpre1
Gene length1386 bp
IdentifierMb3819
Location 4172074 bp
Protein summary information
Molecular mass50163.2 Da
Isoelectric point7.769
Protein length461 amino acids
Orthologs
M. tuberculosis MTBC0mtbc0_004018
M. tuberculosis H37RvRv3790
Cross-references
InterProIPR006094, IPR007173, IPR016166, IPR016169
UniProtKB/TrEMBLQ7TVN6
SWISS-MODELA0A1R3Y598
General annotation
TypeCDS
FunctionUnknown
Productdecaprenylphosphoryl-beta-d-ribose 2'-oxidase
CommentsMb3819, -, len: 461 aa. Equivalent to Rv3790, len: 461 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 461 aa overlap). Probable oxidoreductase (EC 1.-.-.-), equivalent to Q9CDA4|ML0109 PUTATIVE FAD-LINKED OXIDOREDUCTASE from Mycobacterium leprae (460 aa), FASTA scores: opt: 2722, E(): 1.4e-161,(86.55% identity in 461 aa overlap). Also highly similar to others e.g. Q9KZA4|SC5G8.10c PUTATIVE OXIDOREDUCTASE from Streptomyces coelicolor (457 aa), FASTA scores: opt: 1336, E(): 1.7e-75, (47.1% identity in 452 aa overlap); Q98KY4|MLL1265 PROBABLE OXIDOREDUCTASE from Rhizobium loti (Mesorhizobium loti) (449 aa), FASTA scores: opt: 636,E(): 4.9e-32, (36.0% identity in 439 aa overlap); Q9HDX8|SPAPB1A10.12c PUTATIVE D-ARABINONO-1,4-LACTONE OXIDASE from Schizosaccharomyces pombe (Fission yeast) (461 aa), FASTA scores: opt: 297, E(): 5.6e-11, (23.55% identity in 467 aa overlap); etc. C-terminal end has a high similarity to Q9AQD0 PUTATIVE OXIDOREDUCTASE (FRAGMENT) from Mycobacterium smegmatis (149 aa) FASTA scores: opt: 901, E(): 6.5e-49, (86.6% identity in 149 aa overlap).
Functional categoryLipid metabolism
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS41720744173459+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3819|dpre1
MLSVGATTTATRLTGWGRTAPSVANVLRTPDAEMIVKAVARVAESGGGRGAIARGLGRSYGDNAQNGGGLVIDMTPLNTIHSIDADTKLVDIDAGVNLDQLMKAALPFGLWVPVLPGTRQVTVGGAIACDIHGKNHHSAGSFGNHVRSMDLLTADGEIRHLTPTGEDAELFWATVGGNGLTGIIMRATIEMTPTSTAYFIADGDVTASLDETIALHSDGSEARYTYSSAWFDAISAPPKLGRAAVSRGRLATVEQLPAKLRSEPLKFDAPQLLTLPDVFPNGLANKYTFGPIGELWYRKSGTYRGKVQNLTQFYHPLDMFGEWNRAYGPAGFLQYQFVIPTEAVDEFKKIIGVIQASGHYSFLNVFKLFGPRNQAPLSFPIPGWNICVDFPIKDGLGKFVSELDRRVLEFGGRLYTAKDSRTTAETFHAMYPRVDEWISVRRKVDPLRVFASDMARRLELL
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