Gene Mb3846c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3846c
Gene length780 bp
IdentifierMb3846c
Location 4217065 bp
Protein summary information
Molecular mass28453.9 Da
Isoelectric point10.5902
Protein length259 amino acids
Orthologues
M. tuberculosisRv3816c
Cross-references
InterProIPR002123
UniProtKB/TrEMBLQ7TVL7
General annotation
TypeCDS
FunctionUnknown
Productpossible acyltransferase
CommentsMb3846c, -, len: 259 aa. Equivalent to Rv3816c,len: 259 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 259 aa overlap). Possible acyltransferase (EC 2.3.1.-), equivalent to Q9CDC0|ML0087 PUTATIVE ACYLTRANSFERASE from Mycobacterium leprae (257 aa) FASTA scores: opt: 1401, E(): 1.5e-80, (81.9% identity in 254 aa overlap). Also highly similar to many putative acyltransferases and hypothetical proteins e.g. Q9K3R3|2SCG4.01 PUTATIVE ACYLTRANSFERASE from Streptomyces coelicolor (242 aa), FASTA scores: opt: 758, E(): 2.4e-40,(51.7% identity in 234 aa overlap); Q9ZBS1|SC7A1.02 PUTATIVE ACYLTRANSFERASE from Streptomyces coelicolor (264 aa), FASTA scores: opt: 312, E(): 2e-12, (29.55% identity in 237 aa overlap); O67841|AAS|AQ_2058 2-ACYLGLYCEROPHOSPHOETHANOLAMINE ACYLTRANSFERASE from Aquifex aeolicus (211 aa), FASTA scores: opt: 281, E(): 1.5e-10, (32.7% identity in 162 aa overlap); etc. Also highly similar to upstream ORFs O07808|Rv3815c|MTCY409.15 PUTATIVE ACYLTRANSFERASE from Mycobacterium tuberculosis (251 aa), FASTA scores: opt: 847, E(): 6.7e-46, (55.7% identity in 246 aa overlap); and O07809|Rv3814c|MTCY409.16 PUTATIVE ACYLTRANSFERASE from Mycobacterium tuberculosis (261 aa), FASTA scores: opt: 776, E(): 1.9e-41, (50.9% identity in 228 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42170654217844-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3846c|Mb3846c
MEPVYGTVIRLARLSWRIQGLKITVTGVDNLPTSGGAVVAINHTSYLDFTFAGLPAYQQGLGRKVRFMAKQEVFDHKITGPIMRSLRHIPVDRQDGSASYDAAVRMLKAGELVGVYPEATISRSFEIKEFKTGAARMAIEAGVPIVPHIVWGAQRIWTKDRPKKLFRPKVPVTIVVGERIEPTLPTAELNGLLHSRMQHLLERAQELYGPHPAGEFWVPHRLGGGAPSLAEAARLDAQEAAVRAARRAQRAHPAGAPEQ
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