Gene Mb3856 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namefadD23
Gene length1755 bp
IdentifierMb3856
Location 4236085 bp
Protein summary information
Molecular mass62840.8 Da
Isoelectric point5.3526
Protein length584 amino acids
Cross-references
UniProtKB/TrEMBLX2BPQ7, Q7TVK7
General annotation
TypeCDS
FunctionUnknown
Productprobable fatty-acid-amp ligase fadd23 (fatty-acid-amp synthetase) (fatty-acid-amp synthase)
CommentsMb3856, fadD23, len: 584 aa. Equivalent to Rv3826,len: 584 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 584 aa overlap). Probable fadD23,fatty-acid-CoA synthetase (EC 6.2.1.-), highly similar to P71495 ACYL-COA SYNTHASE from Mycobacterium bovis (582 aa), FASTA scores: opt: 2571, E(): 4.4e-146, (66.15% identity in 576 aa overlap); Q9CD79|FADD28|ML0138 ACYL-COA SYNTHETASE from Mycobacterium leprae (579 aa) FASTA scores: opt: 2520, E(): 4.9e-143, (65.2% identity in 575 aa overlap); P54200|FD21_MYCLE PUTATIVE FATTY-ACID--COA LIGASE (ACYL-COA SYNTHETASE) from Mycobacterium leprae (579 aa), FASTA scores: opt: 2330, E(): 1.1e-131, (60.2% identity in 578 aa overlap); etc. Also highly similar to others from Mycobacterium tuberculosis e.g. P96290|FADD28|Rv2941|MTCY24G1.08c (580 aa), FASTA scores: opt: 2587, E(): 4.9e-147, (66.5% identity in 576 aa overlap); O53903|FADD24|Rv1529|MTV045.03 (584 aa), FASTA scores: opt: 2457, E(): 2.9e-139, (63.35% identity in 584 aa overlap); Q50586|FADD25|Rv1521|MT1572|MTCY19G5.07 (583 aa) FASTA scores: opt: 2389, E(): 3.3e-135, (61.45% identity in 581 aa overlap); etc.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42360854237839+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3856|fadD23
MVSLSIPSMLRQCVNLHPDGTAFTYIDYERDSEGISESLTWSQVYRRTLNVAAEVRRHAAIGDRAVILAPQGLDYIVAFLGALQAGLIAVPLSAPLGGASDERVDAVVRDAKPNVVLTTSAIMGDVVPRVTPPPGIASPPTVAVDQLDLDSPIRSNIVDDSLQTTAYLQYTSGSTRTPAGVMITYKNILANFQQMISAYFADTGAVPPLDLFIMSWLPFYHDMGLVLGVCAPIIVGCGAVLTSPVAFLQRPARWLQLMAREGQAFSAAPNFAFELTAAKAIDDDLAGLDLGRIKTILCGSERVHPATLKRFVDRFSRFNLREFAIRPAYGLAEATVYVATSQAGQPPEIRYFEPHELSAGQAKPCATGAGTALVSYPLPQSPIVRIVDPNTNTECPPGTIGEIWVHGDNVAGGYWEKPDETERTFGGALVAPSAGTPVGPWLRTGDSGFVSEDKFFIIGRIKDLLIVYGRNHSPDDIEATIQEITRGRCAAIAVPSNGVEKLVAIVELNNRGNLDTERLSFVTREVTSAISTSHGLSVSDLVLVAPGSIPITTSGKVRRAECVKLYRHNEFTRLDAKPLQASDL
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