Gene Mb3857c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3857c
Gene length1227 bp
IdentifierMb3857c
Location 4237836 bp
Protein summary information
Molecular mass45852.4 Da
Isoelectric point11.7483
Protein length408 amino acids
Orthologs
M. tuberculosis H37RvRv3827c
Cross-references
InterProIPR001959, IPR021027
UniProtKB/TrEMBLQ7TVK6
SWISS-MODELA0A1R3Y5M6
General annotation
TypeCDS
FunctionUnknown
Productpossible transposase
CommentsMb3857c, -, len: 408 aa. Equivalent to Rv3827c,len: 408 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 408 aa overlap). Possible transposase within IS1537 element, similar to several transposases e.g. O83029|TNPC|DR2324|DR0666|DR0978|DR1381|DR1651|DR1933 TRANSPOSASE from Deinococcus radiodurans(408 aa) FASTA scores: opt: 302, E(): 3.9e-12, (30.75% identity in 358 aa overlap); Q9RXX7|DR0178 PUTATIVE TRANSPOSASE from Deinococcus radiodurans (409 aa), FASTA scores: opt: 297,E(): 8.2e-12, (31.1% identity in 360 aa overlap); P73816|SLR2062 TRANSPOSASE from Synechocystis sp. strain PCC 6803 (400 aa), FASTA scores: opt: 296, E(): 9.3e-12,(30.05% identity in 353 aa overlap); etc. Highly similar to proteins from Mycobacterium tuberculosis e.g. O33333|Rv2791c|MTV002.56c TRANSPOSASE (459 aa) FASTA scores: opt: 2211, E(): 9.4e-136, (87.75% identity in 367 aa overlap); P95117|Rv2978c|MTCY349.09 HYPOTHETICAL 51.4 KDA PROTEIN (459 aa), FASTA scores: opt: 2165, E(): 9e-133, (85.85% identity in 367 aa overlap); Q10809|YS85_MYCTU|Rv2885c|MT2953|MTCY274.16c HYPOTHETICAL 51.3 KDA PROTEIN (460 aa), FASTA scores: opt: 2127, E(): 2.6e-130, (83.95% identity in 368 aa overlap); O0777|Rv0606|MTCY19H5.16c PROBABLE TRANSPOSASE (FRAGMENT) (247 aa), FASTA scores: opt: 1405, E(): 9.3e-84, (85.3% identity in 238 aa overlap); etc.
Functional categoryInsertion seqs and phages
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42378364239062-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3857c|Mb3857c
MMARFEVPEGWCVQAFRFTLDPTEDQARALARHFGARRKAYNWAVATLKADIEAWRVTGIGTVKPSLRVLRKRWNTVKDEVCVNAETGAVWWPECSKEAYADGIGGAVDAYWNWQNSRSGKREGKTMGFPRFKKKGRDQDRVTFTTGAMRVEPDRRHLTLPVVGTVRTHENTRRIERLIATGRARVLAISVRRNGTRLDASVRVLVQRPQQPNVAQPGSRVGVDVGVRRLATVANEAGAVLEEVPNPRPLDAALKELRYASRARSRCTKGSRRYRERTTEISRLHRRVNDVRTHHLHVLTTRLAQTHGHIVVEGLDAAGMLRQKGLPGARARRRGLSDSALGTPRRHLSYKTGWYGSALVVADRWFPSLSVEPTVRPGLARLVAVKRGREAAAWLPNNPETGCKSRDH
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