Gene Mb3859c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3859c
Gene length1611 bp
IdentifierMb3859c
Location 4239671 bp
Protein summary information
Molecular mass57059.2 Da
Isoelectric point7.8273
Protein length536 amino acids
Orthologues
M. tuberculosisRv3829c
Cross-references
UniProtKB/TrEMBLQ7TVK4
SWISS-MODELA0A1R3Y5D4
General annotation
TypeCDS
FunctionUnknown
Productprobable dehydrogenase
CommentsMb3859c, -, len: 536 aa. Equivalent to Rv3829c, len 536 aa, from Mycobacetrium tuberculosis strain H37Rv,(99.8% identity in 536 aa overlap). Probable oxidoreductase dehydrogenase (EC 1.-.-.-), similar to others e.g. Q9A3T1|CC3121 PHYTOENE DEHYDROGENASE-RELATED PROTEIN from Caulobacter crescentus (543 aa), FASTA scores: opt: 607, E(): 9.2e-28, (28.25% identity in 552 aa overlap); Q98FP6|MLR3676 PHYTOENE DEHYDROGENASE from Rhizobium loti (Mesorhizobium loti) (521 aa), FASTA scores: opt: 605, E(): 1.2e-27, (28.2% identity in 546 aa overlap); Q97W24|SSO2422 PHYTOENE DEHYDROGENASE RELATED PROTEIN from Sulfolobus solfataricus (518 aa), FASTA scores: opt: 388, E(): 4.4e-15, (27.35% identity in 530 aa overlap); Q98BS8|MLL5443 PROBABLE DEHYDROGENASE from Rhizobium loti (Mesorhizobium loti) (524 aa), FASTA scores: opt: 374, E(): 2.9e-14, (24.35% identity in aa overlap); etc. Also similar to MTCY493.22c|Rv1432|MTCY493.22c HYPOTHETICAL 50.5 KDA PROTEIN (probable dehydrogenase) from Mycobacterium tuberculosis (25.1% identity in 295 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42396714241281-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3859c|Mb3859c
MTGYDAIVIGAGHNGLTAAVLLQRAGLRTACLDAKRYAGGMASTVELFDGYRFDIAGSVQFPTSSAVSSELGLDSLPTVDLEVMSVALRGVGDDPVVQFTDPTKMLTHLHRVHGADAVTGMAGLLAWSQAPTRALGRFEAGTLPKSFDEMYACATNEFERSAIDDMLFGSVTDVLDRHFPDREKHGALRGSMTVLAVNTLYRGPATPGSAAALAFGLGVPEGDFVRWKKLRGGIGALTTHLSQLLERTGGEVRLRSKVTEIVVDNSRSSARVRGVRTAAGDTLTSPIVVSAIAPDVTINELIDPAVLPSEIRDRYLRIDHRGSYLQMHFALAQPPAFAAPYQALNDPSMQASMGIFCTPEQVQQQWEDCRRGIVPADPTVVLQIPSLHDPSLAPAGKQAASAFAMWFPIEGGSKYGGYGRAKVEMGQNVIDKITRLAPNFKGSILRYTTFTPKHMGVMFGAPGGDYCHALLHSDQIGPNRPGPKGFIGQPIPIAGLYLGSAGCHGGPGITFIPGYNAARQALADRRAANCCVLSGR
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