Gene Mb3870 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3870
Gene length414 bp
IdentifierMb3870
Location 4249841 bp
Protein summary information
Molecular mass14357.2 Da
Isoelectric point4.8095
Protein length137 amino acids
Orthologues
M. tuberculosisRv3840
Cross-references
InterProIPR004474
UniProtKB/TrEMBLQ7TVJ4
SWISS-MODELA0A1R3Y5D3
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN
CommentsMb3870, -, len: 137 aa. Equivalent to Rv3840, len: 137 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 137 aa overlap). Possible transcriptional regulator, highly similar in part to PSR PROTEINS (PENICILLIN BINDING PROTEIN REPRESSORS) e.g. Q47828|PSR PSR PROTEIN from Enterococcus hirae (293 aa) FASTA scores: opt: 221, E(): 2.2e-07, (41.65% identity in 108 aa overlap); O86213|PSRFM PSRFM PROTEIN (FRAGMENT) from Enterococcus hirae (171 aa), FASTA scores: opt: 202,E(): 2.4e-06, (40.75% identity in 108 aa overlap); Q47865|PSR PENICILLIN BINDING PROTEIN REPRESSOR from Enterococcus hirae (148 aa), FASTA scores: opt: 201, E(): 2.5e-06, (51.65% identity in 60 aa overlap); etc. Also highly similar in part to other transcriptional regulators e.g. BAB57524|MSRR PEPTIDE METHIONINE SULFOXIDE REDUCTASE REGULATOR from Staphylococcus aureus subsp. aureus Mu50 (327 aa), FASTA scores: opt: 195, E(): 1.2e-05, (36.7% identity in 109 aa overlap); Q99Q02|MSRR|SA1195 PEPTIDE METHIONINE SULFOXIDE REDUCTASE REGULATOR from Staphylococcus aureus subsp. aureus N315, and Staphylococcus aureus (327 aa), FASTA scores: opt: 192,E(): 1.9e-05, (36.7% identity in 109 aa overlap); Q9K6Q8|LYTR|BH3670 ATTENUATOR FOR LYTABC AND LYTR EXPRESSION from Bacillus halodurans (304 aa), FASTA scores: opt: 171, E(): 0.00041, (34.5% identity in 113 aa overlap); etc.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42498414250254+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3870|Mb3870
MAGCIQRFSHVRCLGPGLASDNPTTLISIPRDSYVPIPGHGRDKINAAFALGGGRLLTQTVELATGLHLDHYAEVGFSEFADLVDAFDPLAGVDLPAGCQTLDGRAALGYVRTRATPRADLEGSDVPVPAAAFETQP
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