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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productconserved protein
CommentsMb3890, -, len: 390 aa. Equivalent to Rv3860, len: 390 aa, from Mycobacterium tuberculosis strain H37Rv,(99.7% identity in 390 aa overlap). Conserved hypothetical protein, showing similarity with hypothetical proteins from Mycobacterium leprae e.g. Q9CDD8|ML0048 (586 aa),FASTA scores: opt: 484, E(): 5.5e-14, (29.95% identity in 407 aa overlap); O33082|MLCB628.11c (478 aa) FASTA scores: opt: 484, E(): 4.8e-14, (29.95% identity in 407 aa overlap); etc. Also some similarity with O86637|SC3C3.03c HYPOTHETICAL 112.1 KDA PROTEIN from Streptomyces coelicolor(1083 aa), FASTA scores: opt: 483, E(): 9.6e-14,(30.45% identity in 404 aa overlap). And some similarity with other proteins from Mycobacterium tuberculosis (strains H37Rv and CDC1551) e.g. O05456|Rv3888c|MTCY15F10.24 HYPOTHETICAL 37.7 KDA PROTEIN (341 aa), FASTA scores: opt: 603, E(): 2.8e-19, (35.2% identity in 284 aa overlap); O06396|Rv0530|MTCY25D10.09 HYPOTHETICAL 43.0 KDA PROTEIN (405 aa), FASTA scores: opt: 538, E(): 2e-16, (31.0% identity in 371 aa overlap); O69740|Rv3876|MTV027.11 (666 aa), FASTA scores: opt: 475,E(): 1.5e-13, (30.2% identity in 391 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS42730504274222+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3890|Mb3890
MYERDEFLRDRIRPHQPGTPRGYSPRPPSGDRCPAPPPGRHAAAATPPGPPRLPSAPLRPLPDPAWPRQPEAPPPSTWADPALAPIRSRTRPGERGWRRMVRLVTFGLVGLGRSGMQRQEAQFEATIRTVLHGNHKVAVLGKGGVGKTSVAACVGSILAELRQQDRIVGIDADTAFGRLSSRIDPRAAGSFWELTTDTNLRSFTDITARLGRNSAGLYVLAGQPASGPRRALDPAIYREAALRLDHHFAISVIDCGSSMEAAVTQEVLRDVDALIVVSSPWADGASAAANTIEWLSDYGLTGLLRRSIVVLNDSDGHADKRTKSLLAQEFIDHGQPVVEVPFDPHLRPGGVIDMSHEMAPTTRLKILQVAATVTAYFASRPADAHGSPPR
      
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