Gene Mb3901
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | esx conserved component ecccb1. esx-1 type vii secretion system protein. |
| Comments | Mb3901, -, len: 591 aa. Equivalent to Rv3871, len: 591 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 591 aa overlap). Conserved hypothetical protein, equivalent to Q9CDD7|ML0052 HYPOTHETICAL PROTEIN from Mycobacterium leprae (597 aa) FASTA scores: opt: 3341, E(): 9.8e-192, (80.85% identity in 596 aa overlap); and O33086|MLCB628.15c HYPOTHETICAL PROTEIN from Mycobacterium leprae (597 aa), FASTA scores: opt: 3329, E(): 5.1e-191, (80.55% identity in 596 aa overlap). And similar to C-terminal end of others e.g. Q9Z5I2|ML1543|MLCB596.28 POSSIBLE SPOIIIE-FAMILY MEMBRANE PROTEIN from Mycobacterium leprae (1345 aa), FASTA scores: opt: 601, E(): 5.6e-28, (32.3% identity in 613 aa overlap); O86653|SC3C3.20c ATP/GTP BINDING PROTEIN from Streptomyces coelicolor (1321 aa), FASTA scores: opt: 977,E(): 2.1e-50, (35.15% identity in 583 aa overlap); Q9L0T6|SCD35.15c PUTATIVE CELL DIVISION-RELATED PROTEIN from Streptomyces coelicolor (1525 aa), FASTA scores: opt: 414, E(): 9e-17, (27.6% identity in 424 aa overlap);P71068|YUKA YUKA PROTEIN from Bacillus subtilis (1207 aa), FASTA scores: opt: 343, E(): 1.3e-12, (25.8% identity in 395 aa overlap); etc. And similar to to C-terminal end of hypothetical proteins from Mycobacterium tuberculosis e.g. O06264|Rv3447c|MTCY77.19c (1236 aa) FASTA scores: opt: 845, E(): 1.5e-42, (35.3% identity in 586 aa overlap); O53689|Rv0284|MTV035.12 (1330 aa) FASTA scores: opt: 646, E(): 1.2e-30, (33.35% identity in 606 aa overlap); O53935|Rv1784|MTV049.06 (932 aa) FASTA scores: opt: 589, E(): 2.1e-27, (33.1% identity in 619 aa overlap); etc. Contains 2 X PS00017 ATP/GTP-binding site motif A (P-loop). Note some similarity (with hypothetical proteins from Mycobacterium tuberculosis and P71068|YUKA) continues in upstream ORF MTV027.05. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4285147 | 4286922 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3901|ecccb1
MTAEPEVRTLREVVLDQLGTAESRAYKMWLPPLTNPVPLNELIARDRRQPLRFALGIMDEPRRHLQDVWGVDVSGAGGNIGIGGAPQTGKSTLLQTMVMSAAATHSPRNVQFYCIDLGGGGLIYLENLPHVGGVANRSEPDKVNRVVAEMQAVMRQRETTFKEHRVGSIGMYRQLRDDPSQPVASDPYGDVFLIIDGWPGFVGEFPDLEGQVQDLAAQGLAFGVHVIISTPRWTELKSRVRDYLGTKIEFRLGDVNETQIDRITREIPANRPGRAVSMEKHHLMIGVPRFDGVHSADNLVEAITAGVTQIASQHTEQAPPVRVLPERIHLHELDPNPPGPESDYRTRWEIPIGLRETDLTPAHCHMHTNPHLLIFGAAKSGKTTIAHAIARAICARNSPQQVRFMLADYRSGLLDAVPDTHLLGAGAINRNSASLDEAVQALAVNLKKRLPPTDLTTAQLRSRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTCQMSQAYKATMDKFVGAAFGSGAPTMFLSGEKQEFPSSEFKVKRRPPGQAFLVSPDGKEVIQAPYIEPPEEVFAAPPSAG
Bibliography
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