Gene Mb3914c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | esx conserved component ecca2. esx-2 type vii secretion system protein. probable cbxx/cfqx family protein. |
| Comments | Mb3914c, -, len: 619 aa. Equivalent to Rv3884c,len: 619 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 619 aa overlap). Putative CBXX/CFQX protein family, similar to hypothetical proteins from Mycobacterium leprae e.g. Q9CD28|Y282_MYCLE|ML2537 (640 aa), FASTA scores: opt: 725, E(): 2.9e-34, (28.95% identity in 587 aa overlap); O33089|Y2G8_MYCLE|ML0055|MLCB628.18c (BELONGS TO THE CBXX/CFQX FAMILY) (573 aa); Q9CBV5|ML1536 (610 aa) FASTA scores: opt: 648, E(): 7.4e-30, (31.5% identity in 549 aa overlap). Also similar to proteins belonging to the CBXX/CFQX FAMILY e.g. Q9RKZ2|SC6D7.05c PUTATIVE CBXX/CFQX FAMILY PROTEIN from Streptomyces coelicolor (618 aa) FASTA scores: opt: 557, E(): 1.3e-24, (28.6% identity in 601 aa overlap); P27643|SP5K_BACSU|SPOVK|SPOVJ STAGE V SPORULATION PROTEIN K from Bacillus subtilis (322 aa) FASTA scores: opt: 485, E(): 1.1e-20, (35.0% identity in 280 aa overlap) (similarity only at C-terminus); Q9KAC6|BH2363 STAGE V SPORULATION PROTEIN K from Bacillus halodurans (315 aa), FASTA scores: opt: 462, E(): 2.2e-19,(36.05% identity in 244 aa overlap) (similarity only at C-terminus); etc. And similar to hypothetical proteins from Mycobacterium tuberculosis belonging to the CBXX/CFQX FAMILY e.g. O53687|Y282_MYCTU|Rv0282|MT0295|MTV035.10 HYPOTHETICAL 68.1 KDA PROTEIN (631 aa), FASTA scores: opt: 743, E(): 2.6e-35, (29.9% identity in 612 aa overlap); O69733|Y2G8_MYCTU|Rv3868|MT3981|MTV027.03 HYPOTHETICAL 62.4 KDA PROTEIN (573 aa), FASTA scores: opt: 678, E(): 1.3e-31, (31.25% identity in 589 aa overlap); O53947|YH98_MYCTU|Rv1798|MT1847|MTV049.20 (610 aa) FASTA scores: opt: 669, E(): 4.6e-31, (30.95% identity in 549 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop). SEEMS TO BELONG TO THE CBXX/CFQX FAMILY. |
| Functional category | Cell wall and cell processes |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 4301344 | 4303203 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3914c|ecca2
MSRMVDTMGDLLTARRHFDRAMTIKNGQGCVAALPEFVAATEADPSMADAWLGRIACGDRDLASLKQLNAHSEWLHRETTRIGRTLAAEVQLGPSIGITVTDASQVGLALSSALTIAGEYAKADALLANRELLDSWRNYQWHQLARAFLMYVTQRWPDVLSTAAEDLPPQAIVMPAVTASICALAAHAAAHLGQGRVALDWLDRVDVIGHSRSSGRFGADVLTAAIGPADIPLLVADLAYVRGMVYRQLHEEDKAQIWLSKATINGVLTDAAKEALADPNLRLIVTDERTIASRSDRWDASTAKSRDQLDDDNAAQRRGELLAEGRELLAKQVGLAAVKQAVSALEDQLEVRMMRLEHGLPVEGQTNHMLLVGPPGTGKTTTAEALGKIYAGMGIVRHPEIREVRRSDFCGHYIGESGPKTNELIEKSLGRIIFMDEFYSLIERHQDGTPDMIGMEAVNQLLVQLETHRFDFCFIGAGYEDQVDEFLTVNPGLAGRFNRKLRFESYSPVEIVEIGHRYATPRASQLDDAAREVFLDAVTTIRNYTTPSGQHGIDAMQNGRFARNVIERAEGFRDTRVVAQKRAGQPVSVQDLQIITATDIDAAIRSVCSDNRDMAAIVW
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