Gene Mb3925c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameeccb2
Gene length1488 bp
IdentifierMb3925c
Location 4314411 bp
Protein summary information
Molecular mass51528.9 Da
Isoelectric point10.2304
Protein length495 amino acids
Orthologues
M. tuberculosisRv3895c
Cross-references
InterProIPR007795
UniProtKB/TrEMBLQ7TVE5
SWISS-MODELA0A1R3Y5K7
General annotation
TypeCDS
FunctionUnknown
Productesx conserved component eccb2. esx-2 type vii secretion system protein. probable membrane protein.
CommentsMb3925c, -, len: 495 aa. Equivalent to Rv3895c,len: 495 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 495 aa overlap). Possible conserved membrane protein, highly similar to two CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae: Q9Z5I3|ML1544|MLCB596.27 (506 aa), FASTA scores: opt: 1070, E(): 1.4e-53, (39.8% identity in 485 aa overlap); and Q9CD29|ML2536 (552 aa), FASTA scores: opt: 483, E(): 4e-20, (36.85% identity in 499 aa overlap). Also highly similar to various proteins from Mycobacterium tuberculosis e.g. O53933|Rv1782|MTV049.04 HYPOTHETICAL PROTEIN (506 aa), FASTA scores: opt: 1106, E(): 1.2e-55,(41.25% identity in 485 aa overlap); O69734|Rv3869|MTV027.04 HYPOTHETICAL PROTEIN (480 aa),FASTA scores: opt: 795, E(): 6.1e-38, (36.0% identity in 486 aa overlap); O33088|ML0054|MLCB628.17c PUTATIVE MEMBRANE PROTEIN) (481 aa), FASTA scores: opt: 740, E(): 8.3e-35, (35.65% identity in 485 aa overlap); etc.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS43144114315898-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3925c|eccb2
MPLSLSNRDQNSGHLFYNRRLRAATTRFSVRMKHDDRKQTAALALSMVLVAIAAGWMMLLNVLKPTGIVGDSAIIGDRDSGALYARIDGRLYPALNLTSARLATGTAGQPTWVKPAEIAKYPTGPLVGIPGAPAAMPVNRGAVSAWAVCDTAGRPRSADKPVVTSIAGPITGGGRATHLRDDAGLLVTFDGSTYVIWGGKRSQIDPTNRAVTLSLGLDPGVTSPIQISRALFDGLPATEPLRVPAVPEAGTPSTWVPGARVGSVLQAQTAGGGSQFYVLLPDGVQKISSFVADLLRSANSYGAAAPRVVTPDVLVHTPQVTSLPVEYYPAGRLNFVDTAADPTTCVSWEKASTGPQARVAVYNGRGLPVPPSMDSRIVRLVRDDRAPASVVATQVLVLPGAANFVTSTSGVITAESRESLFWVSGNGVRFGIANDEATLRALGLDPGAAVQAPWPLLRTFAAGPALSRDAALLARDTVPTLGQVAIVTTTAKAGA
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