Gene Rv1684 in Mycobacterium tuberculosis H37Rv
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameRv1684
Gene length225 bp
IdentifierRv1684
Location 1910586 bp
Protein summary information
Molecular mass8289.54 Da
Isoelectric point4.3185
Protein length74 amino acids
Structural information
PFAMO33186
Orthologs
M. leprae TNML1347
M. marinum MMMAR_2479
M. smegmatis MC2-155MSMEG_3764
M. bovis AF2122-97Mb1710A
M. tuberculosis 18bMT18B_2190
M. tuberculosis MTBC0mtbc0_001792
Cross-references
UniProtO33186
SWISS-MODELO33186
TB databaseRv1684
Interacting Drugs/Compounds
TDR TargetsLink
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionFunction unknown
ProductConserved hypothetical protein
CommentsRv1684, (MTCI125.06), len: 74 aa. Conserved hypothetical protein, similar to P75844|YCAR_ECOLI Protein YCAR from Escherichia coli (60 aa), FASTA scores: opt: 108, E(): 0.00022, (39.0% identity in 59 aa overlap).
Functional categoryConserved hypotheticals
ProteomicsIdentified in the culture supernatant of M. tuberculosis H37Rv using mass spectrometry (See Mattow et al., 2003).
MutantEssential gene for in vitro growth of H37Rv in a MtbYM rich medium, by Himar1 transposon mutagenesis (see Minato et al. 2019).Disruption of this gene results in growth defect of H37Rv in vitro, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS19105861910810+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv1684|Rv1684
MLDEALLAILVCPADRGPLVLVEDGDIQVLYNPRLRRAYRIEDGIPVLLVDEAREVDEDEHARLMARGRPAAPQ
Bibliography