Gene Rv2395A in Mycobacterium tuberculosis H37Rv
Go to browser
virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaprA
Gene length216 bp
IdentifierRv2395A
Location 2692224 bp
Protein summary information
Molecular mass7909.05 Da
Isoelectric point11.589
Protein length71 amino acids
Structural information
PFAMQ8VJK0
Orthologs
M. bovis AF2122-97Mb2417A
M. tuberculosis MTBC0mtbc0_002549
Cross-references
UniProtV5QPR9
SWISS-MODELV5QPR9
TB databaseRv2395A
Interacting Drugs/Compounds
TDR TargetsLink
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductAcid and phagosome regulated protein A AprA
CommentsRv2395A, len: 71 aa. AprA, acid and phagosome regulated protein A, restricted to M. tuberculosis complex. Note completely overlapped by sRNA mcr7.
Functional categoryConserved hypotheticals
MutantDisruption of this gene provides a growth advantage for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26922242692439+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv2395A|aprA
LTMTASVAKVTAARPEPSAAWAEARRRVRQRREDMLRHPAFLSKQLPAEPADDDGVAAVYDIAIARRRRPA
Bibliography