Gene Rv2395B in Mycobacterium tuberculosis H37Rv
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameaprB
Gene length165 bp
IdentifierRv2395B
Location 2692551 bp
Protein summary information
Molecular mass5722.64 Da
Isoelectric point4.4811
Protein length54 amino acids
Structural information
PFAMQ8VJJ9
Orthologs
M. bovis AF2122-97Mb2417B
M. tuberculosis MTBC0mtbc0_002550
Cross-references
UniProtV5QRX2
TB databaseRv2395B
Interacting Drugs/Compounds
TDR TargetsLink
Precomputed results
BLASTReport
General annotation
TypeCDS
FunctionUnknown
ProductAcid and phagosome regulated protein B AprB
CommentsRv2395B, len: 54 aa. AprB, acid and phagosome regulated protein B, restricted to M. tuberculosis complex.
Functional categoryConserved hypotheticals
MutantDisruption of this gene provides a growth advantage for in vitro growth of H37Rv, by analysis of saturated Himar1 transposon libraries (see DeJesus et al. 2017).
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26925512692715+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium tuberculosis H37Rv|Rv2395B|aprB
VPGLVPAMPLDALRPARQPTSGLGECATMRRPEAGNEKVAVIWESLDVVPPESL
Bibliography